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Case Reports
. 2020 Apr 30;9(4):2107-2110.
doi: 10.4103/jfmpc.jfmpc_192_20. eCollection 2020 Apr.

Cerebral venous sinus thrombosis-A primer for emergency physician

Subhankar Chatterjee  1 , Chandra Bhushan Sharma  1 , Rishi Tuhin Guria  1 , Souvik Dubey  2 , Carl J Lavie  3
Affiliations
Case Reports

Cerebral venous sinus thrombosis-A primer for emergency physician

Subhankar Chatterjee et al. J Family Med Prim Care. .

Abstract

Cerebral venous sinus thrombosis (CVT) is notoriously known for its varied presentations and extremely high risk of mortality, if remains undetected and untreated. On the other hand, life can be saved with full functional recovery if CVT can be identified with high index of clinical suspicion with supportive imaging and treatment with appropriate anticoagulation. It is important for clinicians to be meticulous to screen for both the potential reversible and heritable causes of CVT so that appropriate measures can be taken to prevent such catastrophe. Here we report a case of CVT involving right sigmoid and transverse sinuses presenting with acute onset left sided hemiplegic without antecedent headache or seizures. Patient was successfully treated with anticoagulants with nearly full functional recovery. Multiple predisposing factors were identified. As per our knowledge, this is the first case of CVT with underlying conglomeration of multiple acquired (lactation, folate deficiency, hyperhomocysteinemia, depot medroxyprogesterone acetate injection) and hereditary risk factors (deficiency of protein C, protein S and antithrombin-III) in a single patient.

Keywords: Anticoagulation; cerebral venous sinus thrombosis; neuroimaging.

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Conflict of interest statement

There are no conflicts of interest.

Figures

Figure 1
Figure 1
NCCT scan brain showing parietal lobe hemorrhage with extensive perilesional edema
Figure 2
Figure 2
MRI brain (GRE sequence) showing blooming suggestive of haemorrhage
Figure 3
Figure 3
Contrast enhanced MRV showing narrow lumen of right sigmoid sinus, right transverse sinus and right internal jugular vein along with fillings defects
See this image and copyright information in PMC

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