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Case Reports
. 2020 Jul;13(7):e011222.
doi: 10.1161/CIRCIMAGING.120.011222. Epub 2020 Jul 15.

COVID-19-Associated Stress (Takotsubo) Cardiomyopathy

Affiliations
Case Reports

COVID-19-Associated Stress (Takotsubo) Cardiomyopathy

Connie W Tsao et al. Circ Cardiovasc Imaging. 2020 Jul.
No abstract available

Keywords: Takotsubo cardiomyopathy; coronavirus; echocardiography; morbidity; stress cardiomyopathy.

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Figures

Figure 1.
Figure 1.. Stress cardiomyopathy during COVID-19 infection.
A. Chest x-ray demonstrated diffuse bilateral pulmonary infiltrates. B. 12-lead ECG acquired within the hour of echocardiogram demonstrated slight ST segment elevations. C. Transthoracic echocardiogram (TTE) demonstrated mid-wall hypokinesis of the left ventricular (LV) with normal contractility of the basal and apical segments, and normal right ventricular systolic function (L-R: 4-chamber, 3-chamber, and 2-chamber images; top panel: end-diastole; bottom: end-systole). D. Short axis TTE images demonstrate normal contractility of LV basal and apical segments and hypokinesis of the mid-ventricular segments (L-R: Basal, mid, and apical images; top panel: end-diastole; bottom: end-systole). Yellow contours in C and D outline the LV endocardial borders.
Figure 1.
Figure 1.. Stress cardiomyopathy during COVID-19 infection.
A. Chest x-ray demonstrated diffuse bilateral pulmonary infiltrates. B. 12-lead ECG acquired within the hour of echocardiogram demonstrated slight ST segment elevations. C. Transthoracic echocardiogram (TTE) demonstrated mid-wall hypokinesis of the left ventricular (LV) with normal contractility of the basal and apical segments, and normal right ventricular systolic function (L-R: 4-chamber, 3-chamber, and 2-chamber images; top panel: end-diastole; bottom: end-systole). D. Short axis TTE images demonstrate normal contractility of LV basal and apical segments and hypokinesis of the mid-ventricular segments (L-R: Basal, mid, and apical images; top panel: end-diastole; bottom: end-systole). Yellow contours in C and D outline the LV endocardial borders.
Figure 1.
Figure 1.. Stress cardiomyopathy during COVID-19 infection.
A. Chest x-ray demonstrated diffuse bilateral pulmonary infiltrates. B. 12-lead ECG acquired within the hour of echocardiogram demonstrated slight ST segment elevations. C. Transthoracic echocardiogram (TTE) demonstrated mid-wall hypokinesis of the left ventricular (LV) with normal contractility of the basal and apical segments, and normal right ventricular systolic function (L-R: 4-chamber, 3-chamber, and 2-chamber images; top panel: end-diastole; bottom: end-systole). D. Short axis TTE images demonstrate normal contractility of LV basal and apical segments and hypokinesis of the mid-ventricular segments (L-R: Basal, mid, and apical images; top panel: end-diastole; bottom: end-systole). Yellow contours in C and D outline the LV endocardial borders.
Figure 2.
Figure 2.. Recovery of stress cardiomyopathy during clinical improvement.
Panels A-C demonstrate data obtained on the day of extubation, 10 days following data in Figure 1. A. CXR continued to demonstrate pulmonary infiltrates. B. ECG abnormalities had normalized compared to prior. C. TTE demonstrated recovery of LV systolic function with resolution of regional dysfunction (L-R: 4-chamber and short-axis basal, mid, and apical images; top panel: end-diastole; bottom: end-systole). Yellow contours outline the LV endocardial borders.
Figure 2.
Figure 2.. Recovery of stress cardiomyopathy during clinical improvement.
Panels A-C demonstrate data obtained on the day of extubation, 10 days following data in Figure 1. A. CXR continued to demonstrate pulmonary infiltrates. B. ECG abnormalities had normalized compared to prior. C. TTE demonstrated recovery of LV systolic function with resolution of regional dysfunction (L-R: 4-chamber and short-axis basal, mid, and apical images; top panel: end-diastole; bottom: end-systole). Yellow contours outline the LV endocardial borders.

Comment in

References

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    1. Medina de Chazal H, Del Buono MG, Keyser-Marcus L, Ma L, Moeller FG, Berrocal D and Abbate A. Stress Cardiomyopathy Diagnosis and Treatment: JACC State-of-the-Art Review. J Am Coll Cardiol. 2018;72:1955–1971. - PMC - PubMed
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