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. 2020 Sep 15;142(11):1120-1122.
doi: 10.1161/CIRCULATIONAHA.120.049252. Epub 2020 Jul 14.

COVID-19: Myocardial Injury in Survivors

Daniel S Knight #  1   2 , Tushar Kotecha #  1 , Yousuf Razvi  1 , Liza Chacko  1   3 , James T Brown  1   2 , Paramjit S Jeetley  1 , James Goldring  1 , Michael Jacobs  1 , Lucy E Lamb  1   4 , Rupert Negus  1 , Anthony Wolff  1 , James C Moon  2   5 , Hui Xue  6 , Peter Kellman  6 , Niket Patel #  1   2 , Marianna Fontana #  1   3
Affiliations

COVID-19: Myocardial Injury in Survivors

Daniel S Knight et al. Circulation. .
No abstract available

Keywords: COVID-19; edema; gadolinium; magnetic resonance imaging; myocarditis; severe acute respiratory syndrome coronavirus 2; troponin.

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Conflict of interest statement

Disclosures: All authors declare no competing interests directly related to the submitted work.

Figures

Figure.
Figure.. CONSORT diagram of patient selection for CMR (left panel) with examples of CMR study diagnoses (right panel).
The top case shows an example CMR images of a patient with myocarditis. The basal short-axis slice with LGE showed subepicardial scar of the basal inferolateral wall (red arrow) and the corresponding native T1 map demonstrated elevated myocardial T1 in the corresponding area consistent with myocardial scar and/or edema. The middle case shows an example of a potential ischemic etiology for troponin leak. There is anterolateral subendocardial LGE (red arrow) signifying myocardial infarction along with septal inducible myocardial ischemia (asterisk) on quantitative stress perfusion maps performed during adenosine-induced hyperemia. The bottom case shows example CMR images of a patient with a dual diagnosis of extensive inducible myocardial ischemia along with myocarditis. The LGE showed diffuse patchy subepicardial enhancement of the myocardium predominantly in the basal inferolateral wall (red arrows) with the T2 map showing associated myocardial edema. Quantitative stress perfusion maps showed extensive inducible ischemia predominantly in the left anterior descending and right coronary artery territories. Abbreviations: eGFR, estimated glomerular filtration rate; hsTnT, high-sensitivity troponin T; LGE, late gadolinium enhancement; MRI, magnetic resonance imaging; RT-PCR, reverse-transcriptase-polymerase-chain-reaction; SARS-CoV-2, severe acute respiratory syndrome coronavirus 2.
See this image and copyright information in PMC

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