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Comparative Study
. 2020 Oct;98(2):115123.
doi: 10.1016/j.diagmicrobio.2020.115123. Epub 2020 Jul 4.

How many are we missing with ID NOW COVID-19 assay using direct nasopharyngeal swabs? Findings from a mid-sized academic hospital clinical microbiology laboratory

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Comparative Study

How many are we missing with ID NOW COVID-19 assay using direct nasopharyngeal swabs? Findings from a mid-sized academic hospital clinical microbiology laboratory

Phyu M Thwe et al. Diagn Microbiol Infect Dis. 2020 Oct.

Abstract

Here, we retrospectively analyzed the comparative results of 182 paired dry nasopharyngeal swabs tested by Abbott ID NOW and nasopharyngeal swabs in viral transport medium by real-time RT-PCR methods. While the overall agreement was 96.2%, we found that of 15 samples that were tested positive with RT-PCR methods, 7 were missed by ID NOW, resulting in a false-negative rate of 47%.

Keywords: COVID-19, Abbott ID NOW; Dry nasopharyngeal swab; SARS-CoV-2.

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    1. Craney A.R., Velu P., Satlin M.J., Fauntleroy K.A., Callan K., Robertson A. Comparison of two high-throughput reverse transcription-polymerase chain reaction systems for the detection of severe acute respiratory syndrome coronavirus 2. J Clin Microbiol. 2020 doi: 10.1128/jcm.00890-20:JCM.00890-20. - DOI - PMC - PubMed
    1. Harrington A., Cox B., Snowdon J., Bakst J., Ley E., Grajales P. Comparison of Abbott ID now and Abbott m2000 methods for the detection of SARS-CoV-2 from nasopharyngeal and nasal swabs from symptomatic patients. J Clin Microbiol. 2020 doi: 10.1128/jcm.00798-20:JCM.00798-20. - DOI - PMC - PubMed
    1. Lieberman J.A., Pepper G., Naccache S.N., Huang M.-L., Jerome K.R., Greninger A.L. Comparison of commercially available and laboratory developed assays for in vitro detection of SARS-CoV-2 in clinical laboratories. J Clin Microbiol. 2020 doi: 10.1128/jcm.00821-20:JCM.00821-20. - DOI - PMC - PubMed
    1. Moran A., Beavis K.G., Matushek S.M., Ciaglia C., Francois N., Tesic V. The detection of SARS-CoV-2 using the Cepheid Xpert Xpress SARS-CoV-2 and Roche cobas SARS-CoV-2 assays. J Clin Microbiol. 2020 doi: 10.1128/jcm.00772-20:JCM.00772-20. - DOI - PMC - PubMed
    1. Rhoads D.D., Cherian S.S., Roman K., Stempak L.M., Schmotzer C.L., Sadri N. Comparison of Abbott ID now, Diasorin Simplexa, and CDC FDA EUA methods for the detection of SARS-CoV-2 from nasopharyngeal and nasal swabs from individuals diagnosed with COVID-19. J Clin Microbiol. 2020 doi: 10.1128/jcm.00760-20:JCM.00760-20. - DOI - PMC - PubMed

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