Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Editorial
. 2020 Jun;9(3):819-823.
doi: 10.21037/tlcr.2020.03.36.

First-line immune-chemotherapy combination for squamous NSCLC is already a reality

Lizza E L Hendriks  1 , Jessica Menis  2   3 , Jordi Remon  4
Affiliations
Editorial

First-line immune-chemotherapy combination for squamous NSCLC is already a reality

Lizza E L Hendriks et al. Transl Lung Cancer Res. 2020 Jun.
No abstract available

PubMed Disclaimer

Conflict of interest statement

Conflicts of Interest: All authors have completed the ICMJE uniform disclosure form (available at http://dx.doi.org/10.21037/tlcr.2020.03.36). JR serves as the unpaid editorial board member of Translational Lung Cancer Research from Sep. 2019 to Sep. 2021. LELH reports other from boehringer ingelheim, other from BMS, other from Roche, other from BMS, grants from Roche, grants from Boehringer Ingelheim, other from AstraZeneca, personal fees from Quadia, grants from Astra Zeneca, other from Lilly, other from Roche, other from Pfizer, other from MSD, from Takeda, outside the submitted work; JM reports grants, personal fees and other from Boehringer-Ingelheim, grants and other from MSD, grants and other from Roche, grants and other from Astrazeneca, grants and other from Ipsen, grants and other from BMS, outside the submitted work; JR reports other from OSE Pharma, other from AstraZeneca, other from MSD, other from Pfizer, other from Roche, outside the submitted work.

Comment on

  • Pembrolizumab plus Chemotherapy for Squamous Non-Small-Cell Lung Cancer.
    Paz-Ares L, Luft A, Vicente D, Tafreshi A, Gümüş M, Mazières J, Hermes B, Çay Şenler F, Csőszi T, Fülöp A, Rodríguez-Cid J, Wilson J, Sugawara S, Kato T, Lee KH, Cheng Y, Novello S, Halmos B, Li X, Lubiniecki GM, Piperdi B, Kowalski DM; KEYNOTE-407 Investigators. Paz-Ares L, et al. N Engl J Med. 2018 Nov 22;379(21):2040-2051. doi: 10.1056/NEJMoa1810865. Epub 2018 Sep 25. N Engl J Med. 2018. PMID: 30280635 Clinical Trial.

References

    1. Reck M, Rodriguez-Abreu D, Robinson AG, et al. Updated Analysis of KEYNOTE-024: Pembrolizumab Versus Platinum-Based Chemotherapy for Advanced Non-Small-Cell Lung Cancer With PD-L1 Tumor Proportion Score of 50% or Greater. J Clin Oncol 2019;37:537-46. 10.1200/JCO.18.00149 - DOI - PubMed
    1. Reck M, Rodriguez-Abreu D, Robinson AG, et al. Pembrolizumab versus Chemotherapy for PD-L1-Positive Non-Small-Cell Lung Cancer. N Engl J Med 2016;375:1823-33. 10.1056/NEJMoa1606774 - DOI - PubMed
    1. Mok TSK, Wu YL, Kudaba I, et al. Pembrolizumab versus chemotherapy for previously untreated, PD-L1-expressing, locally advanced or metastatic non-small-cell lung cancer (KEYNOTE-042): a randomised, open-label, controlled, phase 3 trial. Lancet 2019;393:1819-30. 10.1016/S0140-6736(18)32409-7 - DOI - PubMed
    1. Gandhi L, Rodriguez-Abreu D, Gadgeel S, et al. Pembrolizumab plus Chemotherapy in Metastatic Non-Small-Cell Lung Cancer. N Engl J Med 2018;378:2078-92. 10.1056/NEJMoa1801005 - DOI - PubMed
    1. Powell SF, Rodrigeuz-abreu D, Langer C, et al. Pembrolizumab Plus Platinum Based Chemotherapy in NSCLC With Brain Metastases: Pooled Analysis of KEYNOTE 021, 189, and 407. Ann Oncol 2019;30:v602-60. 10.1093/annonc/mdz260.005 - DOI - PubMed