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Editorial
. 2020 Jun;9(3):828-832.
doi: 10.21037/tlcr-20-400.

Keynote 407: the combination of pembrolizumab and chemotherapy cracks the shell of squamous cell lung cancer

Affiliations
Editorial

Keynote 407: the combination of pembrolizumab and chemotherapy cracks the shell of squamous cell lung cancer

Santiago Viteri et al. Transl Lung Cancer Res. 2020 Jun.
No abstract available

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Conflict of interest statement

Conflicts of Interest: All authors have completed the ICMJE uniform disclosure form (available at http://dx.doi.org/10.21037/tlcr-20-400). RR serves as the unpaid Editor-in-Chief of Translational Lung Cancer Research from Jun 2019 to May 2022. SV reports personal fees from AbbVie, personal fees and non-financial support from Bristol-Myers Squibb, personal fees and non-financial support from Roche, personal fees from Merck Sharp & Dohme, non-financial support from OSE Pharma, non-financial support from Merck KGaA, outside the submitted work; CGC reports non-financial support from Merck Sharp & Dohme, non-financial support from Pierre-Fabre Oncology, personal fees from Boehringer Ingelheim, personal fees from Roche, personal fees from Pfizer, outside the submitted work; RR has nothing to disclose, and RR serves as an unpaid Editor-in-Chief of Translational Lung Cancer Research from Jun 2019 to May 2022.

Comment on

  • Pembrolizumab plus Chemotherapy for Squamous Non-Small-Cell Lung Cancer.
    Paz-Ares L, Luft A, Vicente D, Tafreshi A, Gümüş M, Mazières J, Hermes B, Çay Şenler F, Csőszi T, Fülöp A, Rodríguez-Cid J, Wilson J, Sugawara S, Kato T, Lee KH, Cheng Y, Novello S, Halmos B, Li X, Lubiniecki GM, Piperdi B, Kowalski DM; KEYNOTE-407 Investigators. Paz-Ares L, et al. N Engl J Med. 2018 Nov 22;379(21):2040-2051. doi: 10.1056/NEJMoa1810865. Epub 2018 Sep 25. N Engl J Med. 2018. PMID: 30280635 Clinical Trial.

References

    1. Paz-Ares L, Luft A, Vicente D, et al. Pembrolizumab plus Chemotherapy for Squamous Non-Small-Cell Lung Cancer. N Engl J Med 2018;379:2040-51. 10.1056/NEJMoa1810865 - DOI - PubMed
    1. Stewart PA, Welsh EA, Slebos RJC, et al. Proteogenomic landscape of squamous cell lung cancer. Nat Commun 2019;10:3578. 10.1038/s41467-019-11452-x - DOI - PMC - PubMed
    1. Available online: https://www.fda.gov/drugs/fda-approves-pembrolizumab-combination-chemoth...
    1. Available online: https://www.ema.europa.eu/en/documents/variation-report/keytruda-h-c-382...
    1. Brahmer JR, Govindan R, Anders RA, et al. The Society for Immunotherapy of Cancer consensus statement on immunotherapy for the treatment of non-small cell lung cancer (NSCLC). J Immunother Cancer 2018;6:75. 10.1186/s40425-018-0382-2 - DOI - PMC - PubMed