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Review
. 2020 Jun;9(3):1510-1517.
doi: 10.21037/tau.2019.09.20.

Current techniques of prostate biopsy: an update from past to present

Mohamed Essam Noureldin  1   2   3 , Martin J Connor  1 , Nicholas Boxall  4 , Saiful Miah  4 , Taimur Shah  1   2 , Jochen Walz  5
Affiliations
Review

Current techniques of prostate biopsy: an update from past to present

Mohamed Essam Noureldin et al. Transl Androl Urol. 2020 Jun.

Abstract

Knowing the demerits of the transrectal ultrasound guided biopsy has led to a shift in the general techniques and technology of the prostate biopsy. In addition, the advances in magnetic resonance imaging (MRI) sensitivity and the evidence from the PROMIS trial about its ability to detect clinically significant tumours encourage urologists and industry to implement MRI-guided targeted biopsy. However, the science is still looking how to improve safety and increase its cancer detection rate (CDR).

Keywords: Prostate cancer; biopsy; grade; magnetic resonance imaging (MRI); prostate neoplasm.

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Conflict of interest statement

Conflicts of Interest: All authors have completed the ICMJE uniform disclosure form (available at http://dx.doi.org/10.21037/tau.2019.09.20). The series “Prostate Imaging and Focal Therapy” was commissioned by the editorial office without any funding or sponsorship. MJC, SM and TS served as the unpaid Guest Editors of the series. The authors have no other conflicts of interest to declare.

Figures

Figure 1
Figure 1
Evolution of prostate biopsy knowledge following introduction of transrectal ultrasound guided biopsy.
Figure 2
Figure 2
Sextant cores of the TRUS-GB. Total of either 8 (A) or 6 (B) containers. Inking the lateral core in each container can provide additional information regarding orientation (B). TRUS-GB, transrectal ultrasound guided prostate biopsy; LFL, left far lateral; RFL, right far lateral; LB, left base; RB, right base; LM, left mid; RM, right mid; LA, left apex; RA, right apex; LBL, left base lateral; RBL, right base lateral; LML, left mid lateral; RML, right mid lateral; LMM, left mid medial; RMM, right mid medial; LAL, left apex lateral; RAL, right apex lateral; LAM, left apex medial; RAM, right apex medial.
Figure 3
Figure 3
Transperineal prostate biopsy. (A) Prostate; (B) transrectal ultrasound probe; (C) grid; (D) biopsy needle; (E) rectum.
See this image and copyright information in PMC

References

    1. Kasivisvanathan V, Rannikko AS, Borghi M, et al. MRI-Targeted or Standard Biopsy for Prostate-Cancer Diagnosis. N Engl J Med 2018;378:1767-77. 10.1056/NEJMoa1801993 - DOI - PMC - PubMed
    1. Ahmed HU, El-Shater Bosaily A, Brown LC, et al. Diagnostic accuracy of multi-parametric MRI and TRUS biopsy in prostate cancer (PROMIS): a paired validating confirmatory study. Lancet 2017;389:815-22. 10.1016/S0140-6736(16)32401-1 - DOI - PubMed
    1. Sruogis A, Jankevicius F, Mickys U. Prostatic biopsy technique. Historical review. Medicina 2005;41:957-67. - PubMed
    1. Baco E, Rud E, Eri LM, et al. A randomized controlled trial to assess and compare the outcomes of two-core prostate biopsy guided by fused magnetic resonance and transrectal ultrasound images and traditional 12-core systematic biopsy. Eur Urol 2016;69:149-56. 10.1016/j.eururo.2015.03.041 - DOI - PubMed
    1. Giganti F, Moore CM. A critical comparison of techniques for MRI-targeted biopsy of the prostate. In: Transl Androl Urol 2017;6:432-43. 10.21037/tau.2017.03.77 - DOI - PMC - PubMed