R.P.K. has received consulting fees from Haemonetics. P.A.G. receives honoraria for lectures and consultations, including service on speakers' bureaus from Bayer, Merck, Janssen, Medicure, and World Medical, and is receiving grants from the National Institutes of Health, Janssen, Merck, Bayer, Haemonetics, Instrumentation Labs, and Amgen. P.A.G. holds stock or stock options in Merck, Medtronic, and Pfizer, and is holding patents in the area of personalized antiplatelet therapy and interventional cardiology. Other authors report no disclosure.