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Observational Study
. 2021 Mar;16(2):409-418.
doi: 10.1007/s11739-020-02444-7. Epub 2020 Jul 17.

Influence of ventilatory strategies on outcomes and length of hospital stay: assist-control and synchronized intermittent mandatory ventilation modes

Thais Bruno de Godoi  1 , Fernando Augusto Lima Marson  2 , Camila Vantini Capasso Palamim  3   2   4 , Gianna Carla Cannonieri-Nonose  5   6
Affiliations
Observational Study

Influence of ventilatory strategies on outcomes and length of hospital stay: assist-control and synchronized intermittent mandatory ventilation modes

Thais Bruno de Godoi et al. Intern Emerg Med. 2021 Mar.

Abstract

The use of synchronized intermittent mandatory ventilation with pressure support ventilation (SIMV + PSV) mode has been discontinued. This study analyzed the association between medical outcomes related to the use of assist-control (A/C) and SIMV + PSV in an intensive care unit. In this observational and retrospective study, modes of ventilation and medical data were collected from electronic medical records for three consecutive years and were related to medical outcomes (mortality), duration of mechanical ventilation, length of hospital stay and the need for tracheostomy. Participants were divided into groups according to the modes of ventilation: A/C and SIMV + PSV. Statistical analyses were performed in the R environment. Alpha = 0.05. The using chi-square, Fisher's exact, Mann-Whitney and Kruskal-Wallis tests were used. 345 adult participants were included; 211/345 (61.16%) were males. Of the participants, 151/345 (43.77%) were on SIMV + PSV and 194/345 (56.23%) were on A/C. The comparative analysis between the modes of ventilation showed no significant differences in length of hospital stay (p = 0.675), duration of mechanical ventilation (p = 0.952), mortality (p = 0.241), failed extubation (p = 0.411) and the need for tracheostomy (p = 0.301). SIMV + PSV as a mode of ventilation showed similar statistical results to the A/C mode, when compared to analyzed medical outcomes.

Keywords: Intensive care unit; Length of hospital stay; Mechanical ventilation; Mode of ventilation; Mortality; Ventilator weaning.

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Conflict of interest statement

The authors declare that they have no conflict of interest.

Figures

Fig. 1
Fig. 1
Flowchart showing inclusion of patients in the study. A/C assist-control ventilation, SIMV + PSV synchronized intermittent mandatory ventilation with pressure support ventilation
See this image and copyright information in PMC

Comment in

References

    1. Aghadavoudi O, Alikiaii B, Sadeghi F. Comparison of respiratory and hemodynamic stability in patients with traumatic brain injury ventilated by two ventilator modes: pressure regulated volume control versus synchronized intermittent mechanical ventilation. Adv Biomed Res. 2016;5:175. doi: 10.4103/2277-9175.180635. - DOI - PMC - PubMed
    1. Pham T, Brochard LJ, Slutsky AS. Mechanical ventilation: state of the art. Mayo Clin Proc. 2017;92(9):1382–1400. doi: 10.1016/j.mayocp.2017.05.004. - DOI - PubMed
    1. Loss SH, Oliveira RP, Maccari JG, Savi A, Boniatti MM, Hetzel MP, Dallegrave DM, Balzano PC, Oliveira ES, Hoher JÁ, Torelly AP, Teixeira C. The reality of patients requiring prolonged mechanical ventilation: a multicenter study. Rev Bras Ter Intensiva. 2015;27(1):26–35. doi: 10.5935/0103-507X.20150006. - DOI - PMC - PubMed
    1. Kutchak FM, Rieder MM, Victorino JA, Meneguzzi C, Poersch K, Forgiarini Junior LA, Bianchin MM. Simple motor tasks independently predict extubation failure in critically ill neurological patients. J Bras Pneumol. 2017;43(3):183–189. doi: 10.1590/s1806-37562016000000155. - DOI - PMC - PubMed
    1. Antonio ACP, Teixeira C, Castro PS, Zanardo AP, Gazzana MB, Knorst M. Usefulness of radiological signs of pulmonary congestion in predicting failed spontaneous breathing trials. J Bras Pneumol. 2017;43(4):253–258. doi: 10.1590/s1806-37562016000000360. - DOI - PMC - PubMed

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