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. 2020 Nov;125(4):305-310.
doi: 10.1080/03009734.2020.1793039. Epub 2020 Jul 20.

Work at inpatient care units is associated with an increased risk of SARS-CoV-2 infection; a cross-sectional study of 8679 healthcare workers in Sweden

Anna-Karin Lidström  1 , Fredrik Sund  1 , Bo Albinsson  2 , Johan Lindbäck  3 , Gabriel Westman  1
Affiliations

Work at inpatient care units is associated with an increased risk of SARS-CoV-2 infection; a cross-sectional study of 8679 healthcare workers in Sweden

Anna-Karin Lidström et al. Ups J Med Sci. 2020 Nov.

Abstract

Background: During the Covid-19 pandemic, the protection of healthcare workers has been in focus throughout the world, but the availability and quality of personal protective equipment has at times and in some settings been suboptimal.

Materials and methods: A total of 8679 healthcare workers and healthcare support staff in the county of Uppsala, north of Stockholm, were included in this cross-sectional study. All subjects were analysed for IgG anti-SARS-CoV-2, and predictors for positive serostatus were analysed in a logistic regression model including demographic parameters and self-reported employment characteristics.

Results: Overall, 577 (6.6%) were classified as seropositive, with no statistically significant differences between healthcare workers and support staff. Among healthcare workers, age (OR 0.987 per year, 95% CI 0.980-0.995), time to sampling (OR 1.019 per day, 95% CI 1.004-1.035), and employment at an outpatient care unit (OR 0.620, 95% CI 0.487-0.788) were statistically significantly associated with risk of infection. Covid-19 specific units were not at particular risk, compared to other units with comparable characteristics and staff demography.

Conclusion: Our findings indicate that SARS-CoV-2 transmission is related to inpatient healthcare work, and illustrate the need for a high standard of basic hygiene routines in all inpatient care settings.

Keywords: Covid-19; IgG; SARS-CoV-2; healthcare workers; transmission.

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Conflict of interest statement

None of the authors have any disclosures to report in relation to this study.

Figures

Figure 1.
Figure 1.
Density plot illustrating the distribution of IgG anti-SARS-CoV-2. All values shifted 0.01 to allow logarithmic transformation. All subjects included in the analysis.
Figure 2.
Figure 2.
Forest plot of IgG anti-SARS-CoV-2 prevalence. Subgroup prevalence and confidence intervals of IgG anti-SARS-CoV-2 positivity. N is the total number of subjects in each category. All subjects included in the analysis.
Figure 3.
Figure 3.
Univariable logistic modelling of relation between age (Panel A, left) and time to sampling (Panel B, right) and risk of IgG anti-SARS-CoV-2 positivity. All subjects included in analysis.
See this image and copyright information in PMC

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