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. 2021 Feb;54(1):97-100.
doi: 10.1016/j.jmii.2020.07.003. Epub 2020 Jul 10.

Clinical application of rapid diagnostic test kit for SARS-CoV-2 antibodies into the field of patient care

Jae-Hoon Ko  1 , Eun-Jeong Joo  2 , Sung-Han Kim  3 , Yae-Jean Kim  4 , Kyungmin Huh  1 , Sun Young Cho  1 , Cheol-In Kang  1 , Doo Ryeon Chung  1 , Eun-Suk Kang  5 , Kyong Ran Peck  6
Affiliations

Clinical application of rapid diagnostic test kit for SARS-CoV-2 antibodies into the field of patient care

Jae-Hoon Ko et al. J Microbiol Immunol Infect. 2021 Feb.

Abstract

Clinical applicability of rapid diagnostic test kit for SARS-CoV-2 antibodies was evaluated. The kit detected antibodies from day 9-56 of illness. IgG bands were observed up to 1: 1000 dilutions. The kit could detect 90.5% of IgG and 61.9% of IgM antibodies of mild febrile patients without pneumonia.

Keywords: Antibody; Point-of-care test; Rapid diagnostic test; SARS-CoV-2; Titration.

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Conflict of interest statement

Declaration of Competing Interest The authors declare that they have no conflict of interest.

Figures

Figure 1
Figure 1
Tests for application of RDT kit for SARS-CoV-2 antibody into the field of COVID-19 patient management. (a) Tests using specimens from pneumonic COVID-19 patients. (b) Tests for serial specimens from a patient. (c) Tests using convalescent sera from mild febrile COVID-19 patients without pneumonia. (d) Titration tests with ten-fold dilutions of serum specimens. Pictures with larger size are presented as a supplementary material. Abbreviations: RDT, rapid diagnostic kit; SARS-CoV-2, Severe acute respiratory syndrome coronavirus 2; COVID-19, coronavirus disease 2019; WB, whole blood.
See this image and copyright information in PMC

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