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Review
. 2020 Jun 15;19(3):254-264.
doi: 10.1002/rmb2.12332. eCollection 2020 Jul.

Relationship between nutrition and reproduction

Fumitoshi Koga  1 , Shigeki Kitagami  1 , Arisa Izumi  1 , Tomoko Uemura  1 , Osamu Takayama  1 , Tsuyoshi Koga  1 , Toru Mizoguchi  2
Affiliations
Review

Relationship between nutrition and reproduction

Fumitoshi Koga et al. Reprod Med Biol. .

Abstract

Background: Recently, the relationship between nutrition and reproduction is being studied. In particular, when older women receive reproductive treatment, egg aging causes greater problems than organic factors.

Methods: This study investigated the relationship between nutrition and reproduction with a focus on factors that cause aging, including oxidation, glycation, and chronic inflammation. A large volume of data concerning each nutrient's relationship with reproductive medicine was collected from a number of observational studies.

Main findings: The results showed that refined carbohydrates should be avoided and care should be taken to achieve proper intake of omega-3 fatty acids. Folic acid and vitamin D were also effective. For men, antioxidant measures are especially effective. The effects of antioxidants are related to insulin resistance, which causes chronic inflammation.

Conclusion: Recent research has shown that rather than meal content, meal intervals are more important for improving insulin resistance. Future research should examine lifestyle-related nutrition factors and their relationships to reproductive treatment.

Keywords: AGEs; diet; fertility; insulin resistance; nutrition.

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Conflict of interest statement

Conflicts of interest: Fumitoshi Koga, Shigeki Kitagami, Arisa Izumi, Tomoko Uemura, Osamu Takayama, Tsuyoshi Koga, and Toru Mizoguchi declare that they have no conflict of interest. Human rights statements and informed consent: All procedures followed were in accordance with the ethical standards of the responsible committee on human experimentation (institutional and national) and with the Helsinki Declaration of 1975, as revised in 2005. Informed consent was obtained from all patients for being included in the study. Human/animal studies: This article does not contain any studies with human or animal subjects performed by any of the authors.

References

    1. Howard BV, Manson JE, Stefanick ML, et al. Low‐fat dietary pattern and weight change over 7 years: the Women’s Health Initiative Dietary Modification Trial. JAMA. 2006;295:39‐49. - PubMed
    1. United States . Congress. Senate. Select Committee on Nutrition and Human Needs. Dietary goals for the United States, supplemental views, 1977 Washington: U.S. Govt. Print. Off.
    1. Dehghan M, Mente A, Zhang X, Swaminathan SS, Li W. Association of fats and carbohydrate intake with cardiovascular disease and mortality in 18 countries from five continents (PURE): a prospective cohort study. Lancet. 2017;29:2050‐2062. - PubMed
    1. Gaskins AJ, Chiu YH, Williams PL, et al. Maternal whole grain intake and outcomes of in vitro fertilization. Fertil Steril. 2016;105:1503‐1510. - PMC - PubMed
    1. Machtinger R, Gaskins AJ, Mansur A, et al. Association between preconception maternal beverage intake and in vitro fertilization outcome. Ferti Steril. 2017;108:1026‐1033. - PMC - PubMed