Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Editorial
. 2020 Sep 1;202(5):642-644.
doi: 10.1164/rccm.202007-2833ED.

Computed Tomography Vascular Tree-in-Bud: A Novel Prognostic Imaging Biomarker in COVID-19?

Rachel L Eddy  1   2 , Don D Sin  1   2
Affiliations
Editorial

Computed Tomography Vascular Tree-in-Bud: A Novel Prognostic Imaging Biomarker in COVID-19?

Rachel L Eddy et al. Am J Respir Crit Care Med. .
No abstract available

PubMed Disclaimer

Figures

Figure 1.
Figure 1.
Computed tomography (CT) vessel tree-in-bud schematic in coronavirus disease (COVID-19). Compared with normal pulmonary vessels (left), peripheral vessels in COVID-19 (middle) are resolved on CT imaging and demonstrate a tree-in-bud pattern. Hypercoagulability and lack of fibrinolysis in COVID-19 driving pulmonary thrombosis likely enhances the peripheral pulmonary vessels on CT imaging to cause the tree-in-bud pattern, although the direct pathologic cause is not yet determined.
See this image and copyright information in PMC

Comment on

  • Pulmonary Angiopathy in Severe COVID-19: Physiologic, Imaging, and Hematologic Observations.
    Patel BV, Arachchillage DJ, Ridge CA, Bianchi P, Doyle JF, Garfield B, Ledot S, Morgan C, Passariello M, Price S, Singh S, Thakuria L, Trenfield S, Trimlett R, Weaver C, Wort SJ, Xu T, Padley SPG, Devaraj A, Desai SR. Patel BV, et al. Am J Respir Crit Care Med. 2020 Sep 1;202(5):690-699. doi: 10.1164/rccm.202004-1412OC. Am J Respir Crit Care Med. 2020. PMID: 32667207 Free PMC article.

References

    1. World Health Organization (WHO) WHO coronavirus disease (COVID-19) dashboard. 2020 [accessed 2020 Jul 14]. Available from: https://covid19.who.int/
    1. Lax SF, Skok K, Zechner P, Kessler HH, Kaufmann N, Koelblinger C, et al. Pulmonary arterial thrombosis in COVID-19 with fatal outcome: results from a prospective, single-center, clinicopathologic case series. Ann Intern Med. [online ahead of print] 14 May 2020; DOI: 10.7326/M20-2566. - PMC - PubMed
    1. Grasselli G, Zangrillo A, Zanella A, Antonelli M, Cabrini L, Castelli A, et al. COVID-19 Lombardy ICU Network. Baseline characteristics and outcomes of 1591 patients infected with SARS-CoV-2 admitted to ICUs of the Lombardy region, Italy. JAMA. 2020;323:1574–1581. - PMC - PubMed
    1. Ackermann M, Verleden SE, Kuehnel M, Haverich A, Welte T, Laenger F, et al. Pulmonary vascular endothelialitis, thrombosis, and angiogenesis in COVID-19. N Engl J Med. 2020;383:120–128. - PMC - PubMed
    1. Fox SE, Akmatbekov A, Harbert JL, Li G, Quincy Brown J, Vander Heide RS. Pulmonary and cardiac pathology in African American patients with COVID-19: an autopsy series from New Orleans. Lancet Respir Med. 2020;8:681–686. - PMC - PubMed