Machine Learning Classifier Models: The Future for Acute Respiratory Distress Syndrome Phenotyping?

Bairbre McNicholas¹, Michael G Madden², John G Laffey^{1

3

4}

Affiliations

¹ Department of Anaesthesia and Intensive Care Medicine, Galway University Hospitals, Galway, Ireland.
² College of Science and Engineering, National University of Ireland, Galway, Ireland.
³ School of Medicine and.
⁴ Regenerative Medicine Institute at the CURAM Centre for Medical Devices, National University of Ireland, Galway, Ireland.

Editorial

Bairbre McNicholas et al. Am J Respir Crit Care Med. 2020.

. 2020 Oct 1;202(7):919-920.

doi: 10.1164/rccm.202006-2388ED.

Bairbre McNicholas¹, Michael G Madden², John G Laffey^{1

3

4}

¹ Department of Anaesthesia and Intensive Care Medicine, Galway University Hospitals, Galway, Ireland.
² College of Science and Engineering, National University of Ireland, Galway, Ireland.
³ School of Medicine and.
⁴ Regenerative Medicine Institute at the CURAM Centre for Medical Devices, National University of Ireland, Galway, Ireland.

No abstract available

Comment on

Machine Learning Classifier Models Can Identify Acute Respiratory Distress Syndrome Phenotypes Using Readily Available Clinical Data.
Sinha P, Churpek MM, Calfee CS. Sinha P, et al. Am J Respir Crit Care Med. 2020 Oct 1;202(7):996-1004. doi: 10.1164/rccm.202002-0347OC. Am J Respir Crit Care Med. 2020. PMID: 32551817 Free PMC article.

1. McNicholas BA, Rooney GM, Laffey JG. Lessons to learn from epidemiologic studies in ARDS. Curr Opin Crit Care. 2018;24:41–48. - PubMed
1. Bellani G, Laffey JG, Pham T, Fan E, Brochard L, Esteban A, et al. LUNG SAFE Investigators; ESICM Trials Group. Epidemiology, patterns of care, and mortality for patients with acute respiratory distress syndrome in intensive care units in 50 countries. JAMA. 2016;315:788–800. - PubMed
1. Calfee CS, Delucchi K, Parsons PE, Thompson BT, Ware LB, Matthay MA NHLBI ARDS Network. Subphenotypes in acute respiratory distress syndrome: latent class analysis of data from two randomised controlled trials. Lancet Respir Med. 2014;2:611–620. - PMC - PubMed
1. Famous KR, Delucchi K, Ware LB, Kangelaris KN, Liu KD, Thompson BT, et al. ARDS Network. Acute respiratory distress syndrome subphenotypes respond differently to randomized fluid management strategy. Am J Respir Crit Care Med. 2017;195:331–338. - PMC - PubMed
1. Calfee CS, Delucchi KL, Sinha P, Matthay MA, Hackett J, Shankar-Hari M, et al. Irish Critical Care Trials Group. Acute respiratory distress syndrome subphenotypes and differential response to simvastatin: secondary analysis of a randomised controlled trial. Lancet Respir Med. 2018;6:691–698. - PMC - PubMed