Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2020 Dec;26(12):1711-1713.
doi: 10.1016/j.cmi.2020.07.015. Epub 2020 Jul 18.

Non-invasive saliva specimens for the diagnosis of COVID-19: caution in mild outpatient cohorts with low prevalence

Keira Skolimowska  1 , Michael Rayment  2 , Rachael Jones  2 , Pinglawathee Madona  3 , Luke S P Moore  4 , Paul Randell  3
Affiliations

Non-invasive saliva specimens for the diagnosis of COVID-19: caution in mild outpatient cohorts with low prevalence

Keira Skolimowska et al. Clin Microbiol Infect. 2020 Dec.
No abstract available

Keywords: Coronavirus; Diagnostics; SARS-CoV-2; Saliva; Virology.

PubMed Disclaimer

Figures

Fig. 1
Fig. 1
Patient-matched saliva and swab a) raw data table b) SARS-CoV-2 PCR cT values for target A (ORF 1ab), target B (ORF 8) and sample adequacy control (NONO) for 18 patients with SARS-CoV-2 detected by swab. Where SARS-CoV-2 was not detected by saliva, there is no paired cT value. p values calculated by Wilcoxon matched-pairs signed rank test.
See this image and copyright information in PMC

References

    1. Pasomsub E., Watcharananan S.P., Boonyawat K., Janchompoo P., Wongtabtim G., Suksuwan W. Saliva sample as a non-invasive specimen for the diagnosis of coronavirus disease-2019 (COVID-19): a cross-sectional study. Clin Microbiol Infect. 2020 doi: 10.1016/j.cmi.2020.05.001. In press. - DOI - PMC - PubMed
    1. Wyllie A.L., Fournier J., Casanovas-Massana A., Campbell M., Tokuyama M., Vijayakumar P. Saliva is more sensitive for SARS-CoV-2 detection in COVID-19 patients than nasopharyngeal swabs. BMJ Yale. 2020 doi: 10.1101/2020.04.16.20067835. In press. - DOI
    1. Azzi L., Carcano G., Gianfagna F., Grossi P., Gasperina D.D., Genoni A. Saliva is a reliable tool to detect SARS-CoV-2. J Infect. 2020 doi: 10.1016/j.jinf.2020.04.005. In press. - DOI - PMC - PubMed
    1. Williams E., Bond K., Zhang B., Putland M., Williamson D.A. Saliva as a non-invasive specimen for detection of SARS-CoV-2. J Clin Microbiol. 2020 doi: 10.1128/JCM.00776-20. In press. - DOI - PMC - PubMed
    1. Liu Y., Yan L.-M., Wan L., Xiang T.-X., Le A., Liu J.-M. Viral dynamics in mild and severe cases of COVID-19. Lancet Infect Dis. 2020 doi: 10.1016/S1473-3099(20)30232-2. In press. - DOI - PMC - PubMed