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Editorial
. 2020 Jul 20;24(1):449.
doi: 10.1186/s13054-020-03163-3.

Convalescent plasma to treat critically ill patients with COVID-19: framing the need for randomised clinical trials

Manu Shankar-Hari  1   2 , Lise Estcourt  3   4 , Heli Harvala  5   6 , David Roberts  3   4 , David K Menon  7 ; United Kingdom SARS-CoV-2 Convalescent Plasma Evaluation (SCoPE) Consortium
Collaborators, Affiliations
Editorial

Convalescent plasma to treat critically ill patients with COVID-19: framing the need for randomised clinical trials

Manu Shankar-Hari et al. Crit Care. .
No abstract available

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Conflict of interest statement

All authors are involved in randomised clinical trials of convalescent plasma in the UK. No other competing interests declared.

Comment in

References

    1. Andersen KG, Rambaut A, Lipkin WI, Holmes EC, Garry RF. The proximal origin of SARS-CoV-2. Nat Med. 2020;26(4):450–452. doi: 10.1038/s41591-020-0820-9. - DOI - PMC - PubMed
    1. Zhang X, Tan Y, Ling Y, Lu G, Liu F, Yi Z, Jia X, Wu M, Shi B, Xu S, et al. Viral and host factors related to the clinical outcome of COVID-19. Nature. 2020. https://www.nature.com/articles/s41586-020-2355-0. - PubMed
    1. Ni L, Ye F, Cheng ML, Feng Y, Deng YQ, Zhao H, Wei P, Ge J, Gou M, Li X, et al. Detection of SARS-CoV-2-specific humoral and cellular immunity in COVID-19 convalescent individuals. Immunity. 2020;52(6):971–977. doi: 10.1016/j.immuni.2020.04.023. - DOI - PMC - PubMed
    1. Valk SJ, Piechotta V, Chai KL, Doree C, Monsef I, Wood EM, Lamikanra A, Kimber C, McQuilten Z, So-Osman C, et al. Convalescent plasma or hyperimmune immunoglobulin for people with COVID-19: a rapid review. Cochrane Database Syst Rev. 2020;5:CD013600. - PMC - PubMed
    1. Joyner MJ, Wright RS, Fairweather D, Senefeld JW, Bruno KA, Klassen SA, Carter RE, Klompas AM, Wiggins CC, Shepherd JR, et al. Early safety indicators of COVID-19 convalescent plasma in 5,000 patients. J Clin Invest. 2020. https://www.nature.com/articles/s41586-020-2355-0. - PMC - PubMed

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