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. 2020 Jul-Sep;11(3):261-269.
doi: 10.1016/j.jaim.2020.05.005. Epub 2020 Jul 17.

Bhallatakadi Ghrita: Development and evaluation with reference to Murcchana and Shata-Dhauta process

Sandesh R Wayal  1 , Shailendra S Gurav  2
Affiliations

Bhallatakadi Ghrita: Development and evaluation with reference to Murcchana and Shata-Dhauta process

Sandesh R Wayal et al. J Ayurveda Integr Med. 2020 Jul-Sep.

Abstract

Background: Ayurveda is primarily based upon use of herbs either singly or in combination (polyherbal). The cow ghee (clarified butterfat) is considered as a precious base for preparing medicines in Ayurveda. Processing of ghee with plant ingredients is renowned for enhancing their therapeutic efficacy.

Objective: In present research work, the attempt was made to develop cow ghee based Polyherbal Bhallatakadi Ghrita formulations and evaluate them with reference to 'Murcchana' and 'Shata-Dhauta' process.

Materials and methods: The research plants were identified, procured, authenticated and processed. The extracts of plant materials were prepared and used for development of Polyherbal Bhallatakadi Ghrita (PHBG), Polyherbal Bhallatakadi Murcchita Ghrita and Polyherbal Bhallatakadi Shata-Dhauta Ghrita formulations as per Ayurvedic procedures. The prepared ghrita formulations were subjected to organoleptic (colour, odour, taste, appearance and touch), physicochemical (pH, viscosity, moisture content, specific gravity, refractive index, acid value, saponification value, iodine value, peroxide value, Rechert Meissl value and Polenske value) evaluation, in-vitro antioxidant and GC-MS analysis. The accelerated and real time stability studies were carried out to determine shelf life of ghrita formulations.

Results: The results of evaluations indicate that, developed PHBG formulations retained the organoleptic and physicochemical characteristics of ghee. The shelf life of formulations was found to be in the range of 1.6 to 3.3 years at accelerated and 2.2 to 3.8 years at real time stability conditions. All ghrita formulations exhibited antioxidant activity in dose dependent manner.

Conclusion: The standardization or evaluation of Polyherbal Bhallatakadi Ghrita formulations was found to be crucial for the establishment of a steady biological, chemical or simply a quality assurance profile of the drugs.

Keywords: Bhallatakadi; Ghrita; Murcchana; Polyherbal; Shata-Dhauta.

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Conflict of interest statement

Conflicts of interest None.

Figures

Fig. 1
Fig. 1
- Prepared Poly-Herbal Bhallatakadi Ghrita (PHBG) formulations.
Fig. 2
Fig. 2
GC–MS analysis of plain ghee and Polyherbal Bhallatakadi Ghrita (PHBG) formulations. Where A- Plain Ghee, B- Polyherbal Bhallatakadi Ghrita (PHBG-I), C- Polyherbal BhallatakadiMurcchita Ghrita (PHBG-II) and D- Polyherbal BhallatakadiShata-Dhauta Ghrita (PHBG-III).
See this image and copyright information in PMC

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