Plant pan-genomes are the new reference
- PMID: 32690893
- DOI: 10.1038/s41477-020-0733-0
Plant pan-genomes are the new reference
Erratum in
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Author Correction: Plant pan-genomes are the new reference.Nat Plants. 2020 Nov;6(11):1389. doi: 10.1038/s41477-020-00776-y. Nat Plants. 2020. PMID: 33139862
Abstract
Recent years have seen a surge in plant genome sequencing projects and the comparison of multiple related individuals. The high degree of genomic variation observed led to the realization that single reference genomes do not represent the diversity within a species, and led to the expansion of the pan-genome concept. Pan-genomes represent the genomic diversity of a species and includes core genes, found in all individuals, as well as variable genes, which are absent in some individuals. Variable gene annotations often show similarities across plant species, with genes for biotic and abiotic stress commonly enriched within variable gene groups. Here we review the growth of pan-genomics in plants, explore the origins of gene presence and absence variation, and show how pan-genomes can support plant breeding and evolution studies.
References
-
- Tettelin, H. et al. Genome analysis of multiple pathogenic isolates of Streptococcus agalactiae: implications for the microbial "pan-genome". Proc. Natl Acad. Sci. USA 102, 13950–13955 (2005).
-
- Golicz, A. A., Bayer, P. E., Bhalla, P. L., Batley, J. & Edwards, D. Pangenomics comes of age: from bacteria to plant and animal applications. Trends Genet. 36, 132–145 (2020).
-
- Morgante, M., De Paoli, E. & Radovic, S. Transposable elements and the plant pan-genomes. Curr. Opin. Plant Biol. 10, 149–155 (2007).
-
- Golicz, A. A., Batley, J. & Edwards, D. Towards plant pangenomics. Plant Biotechnol. J. 14, 1099–1105 (2016).
-
- Hurgobin, B. & Edwards, D. SNP discovery using a pangenome: has the single reference approach become obsolete? Biology 6, 21 (2017).
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