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Comment
. 2020 Sep;16(9):486-487.
doi: 10.1038/s41581-020-0330-5.

Cell therapy can enable minimization of immunosuppression

Affiliations
Comment

Cell therapy can enable minimization of immunosuppression

James M Mathew et al. Nat Rev Nephrol. 2020 Sep.
No abstract available

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Comment on

  • Regulatory cell therapy in kidney transplantation (The ONE Study): a harmonised design and analysis of seven non-randomised, single-arm, phase 1/2A trials.
    Sawitzki B, Harden PN, Reinke P, Moreau A, Hutchinson JA, Game DS, Tang Q, Guinan EC, Battaglia M, Burlingham WJ, Roberts ISD, Streitz M, Josien R, Böger CA, Scottà C, Markmann JF, Hester JL, Juerchott K, Braudeau C, James B, Contreras-Ruiz L, van der Net JB, Bergler T, Caldara R, Petchey W, Edinger M, Dupas N, Kapinsky M, Mutzbauer I, Otto NM, Öllinger R, Hernandez-Fuentes MP, Issa F, Ahrens N, Meyenberg C, Karitzky S, Kunzendorf U, Knechtle SJ, Grinyó J, Morris PJ, Brent L, Bushell A, Turka LA, Bluestone JA, Lechler RI, Schlitt HJ, Cuturi MC, Schlickeiser S, Friend PJ, Miloud T, Scheffold A, Secchi A, Crisalli K, Kang SM, Hilton R, Banas B, Blancho G, Volk HD, Lombardi G, Wood KJ, Geissler EK. Sawitzki B, et al. Lancet. 2020 May 23;395(10237):1627-1639. doi: 10.1016/S0140-6736(20)30167-7. Lancet. 2020. PMID: 32446407 Free PMC article.

References

    1. Sawitzki, B. et al. Regulatory cell therapy in kidney transplantation (The ONE Study): a harmonised design and analysis of seven non-randomised, single-arm, phase 1/2A trials. Lancet 395, 1627–1639 (2020). - DOI
    1. Sasaki, H. et al. Preclinical and clinical studies for transplant tolerance via the mixed chimerism approach. Hum. Immunol. 79, 258–265 (2018). - DOI
    1. Sykes, M. Immune monitoring of transplant patients in transient mixed chimerism tolerance trials. Hum. Immunol. 79, 334–342 (2018). - DOI
    1. Scandling, J. D. et al. Macrochimerism and clinical transplant tolerance. Hum. Immunol. 79, 266–271 (2018). - DOI
    1. Leventhal, J. R. et al. Updated follow-up of a tolerance protocol in HLA-identical renal transplant pairs given donor hematopoietic stem cells. Hum. Immunol. 79, 277–282 (2018). - DOI

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