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Review
. 2022 Sep;28(9):855-863.
doi: 10.1007/s11655-020-3271-8. Epub 2020 Jul 20.

Research Progress in Chinese Medicine Preparations for Promoting Blood Circulation and Removing Blood Stasis for Cirrhotic Patients with Portal Vein Thrombosis Following Splenectomy

Ding-Qi Zhang  1   2 , Yong-Ping Mu  1   2 , Ying Xu  1   2 , Jia-Mei Chen  1   2 , Ping Liu  1   2   3 , Wei Liu  4   5
Affiliations
Review

Research Progress in Chinese Medicine Preparations for Promoting Blood Circulation and Removing Blood Stasis for Cirrhotic Patients with Portal Vein Thrombosis Following Splenectomy

Ding-Qi Zhang et al. Chin J Integr Med. 2022 Sep.

Abstract

This article presented an overview of the therapeutic effects of Chinese medicine (CM) preparations for promoting blood circulation and removing blood stasis for patients with portal vein thrombosis (PVT) after splenectomy. Based on published clinical researches of CM preparations for PVT after splenectomy in patients with cirrhotic portal hypertension (CPH), this paper evaluated the incidence of PVT, and explored potential active components and mechanisms of CM preparations. Safflower Yellow Injection, Danshen Injection () Danhong Injection (), and Compound Danshen Dropping Pill () achieved good curative effect alone or combined with anticoagulant therapy. In addition, Compound Biejia Ruangan Tablet () and Anluo Huaxian Pill () can also significantly improve the hemodynamic disorders of portal vein system in patients with cirrhosis. Considering the role of CM preparations in ameliorating the incidence of PVT after splenectomy in patients with CPH, we suggested that future research should provide more attention to CM alone or CM combined with anticoagulant for cirrhosis with PVT.

Keywords: Chinese medicine preparations; cirrhotic portal hypertension; portal vein thrombosis; promoting blood circulation and removing blood stasis; splenectomy.

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