The Promise, and Challenges, of Methods to Enhance the External Validity of Randomized Trial Results
- PMID: 32691848
- PMCID: PMC7669659
- DOI: 10.1002/cpt.1992
The Promise, and Challenges, of Methods to Enhance the External Validity of Randomized Trial Results
Conflict of interest statement
Conflict of Interest: The authors declared no competing interests for this work.
Comment on
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Reweighting Randomized Controlled Trial Evidence to Better Reflect Real Life - A Case Study of the Innovative Medicines Initiative.Clin Pharmacol Ther. 2020 Oct;108(4):817-825. doi: 10.1002/cpt.1854. Epub 2020 May 30. Clin Pharmacol Ther. 2020. PMID: 32301116 Free PMC article.
References
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- Rothwell PM (2005). External validity of randomised controlled trials: “To whom do the results of this trial apply?” Lancet 365: 82–93. - PubMed
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- Westreich D, Edwards J, Lesko C, Cole S, and Stuart EA (2019). Target validity and the hierarchy of study designs. American Journal of Epidemiology 188(2): 438–444. https://www.ncbi.nlm.nih.gov/pubmed/30299451 - PMC - PubMed
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- Shadish WR, Cook TD, and Campbell DT (2002). Experimental and quasi-experimental designs for generalized causal inference. Boston, MA: Houghton Mifflin.
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