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Review
. 2021 Feb;93(2):726-732.
doi: 10.1002/jmv.26321. Epub 2020 Jul 28.

HIV/SARS-CoV-2 coinfection: A global perspective

Osman N Kanwugu  1 , Parise Adadi  2
Affiliations
Review

HIV/SARS-CoV-2 coinfection: A global perspective

Osman N Kanwugu et al. J Med Virol. 2021 Feb.

Abstract

Since its first appearance in Wuhan, China, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has rapidly spread throughout the world and has become a global pandemic. Several medical comorbidities have been identified as risk factors for coronavirus disease 2019 (COVID-19). However, it remains unclear whether people living with human immunodefeciency virus (PLWH) are at an increased risk of COVID-19 and severe disease manifestation, with controversial suggestion that HIV-infected individuals could be protected from severe COVID-19 by means of antiretroviral therapy or HIV-related immunosuppression. Several cases of coinfection with HIV and SARS-CoV-2 have been reported from different parts of the globe. This review seeks to provide a holistic overview of SARS-CoV-2 infection in PLWH.

Keywords: COVID-19; HIV; antiretroviral therapy/coinfection; immunodeficiency.

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Conflict of interest statement

The authors declare that there are no conflict of interests.

Figures

Figure 1
Figure 1
Demographic characteristics of HIV/SARS‐CoV‐2 coinfected patients
Figure 2
Figure 2
Disease Severity associated with HIV/SARS‐CoV‐2 coinfected patients
Figure 3
Figure 3
Outcome reported endpoint for HIV/SARS‐CoV‐2 coinfected patients
Figure 4
Figure 4
Common comorbidities associated with HIV/SARS‐CoV‐2 coinfection. CVD, cardiovascular diseases; HLD, hyperlipidemia
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