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Case Reports
. 2020 Jul 14;2020(7):rjaa151.
doi: 10.1093/jscr/rjaa151. eCollection 2020 Jul.

Perianal basal cell carcinoma: a common cancer in an uncommon location

Affiliations
Case Reports

Perianal basal cell carcinoma: a common cancer in an uncommon location

Edward R Hagen et al. J Surg Case Rep. .

Abstract

This is a case of a perianal basal cell carcinoma, a common skin cancer in an unusual location. Our patient is a 67-year-old male with a perianal lesion. He first noticed this painless lesion 5 years prior to presentation and was having fecal incontinence and weight loss. He had a fully encompassing ulcerated lesion involving the entirety of the anal margin. We performed a biopsy that returned on pathology as a basal cell carcinoma. Due to the size of the lesion and his current nutritional status, it was determined to be unresectable. We were able to provide him with a diverting colostomy to address his incontinence and this allowed the patient to recover enough to undergo treatment with radiation (total of 5400 cGy). To our knowledge, this is the largest perianal basal cell carcinoma reported in the literature and an example of combining palliative surgery and radiation as a treatment option.

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Figures

Figure 1
Figure 1
Photograph of the perianal lesion on presentation.
Figure 2
Figure 2
MRI of pelvis showing extension of tumor through the right external sphincter.

References

    1. Cancer Facts & Figures, American Cancer Society 2016. https://www.cancer.org/research/cancer-facts-statistics/all-cancer-facts... (23 July 2019, date last accessed).
    1. Pellegrini C, Maturo MG, Nardo LD, Ciciarelli V, Garcia-Rodrigo CG, Fargnoli MC. Understanding the molecular genetics of basal cell carcinoma. Int J Mol Sci 2017;18:2485. doi: 10.3390/ijms18112485. - DOI - PMC - PubMed
    1. Vitasa BC, Taylor HR, Strickland PT, Rosenthal FS, West S, Abbey H, et al. . Association of nonmelanoma skin cancer and actinic keratosis with cumulative solar ultraviolet exposure in Maryland watermen. Cancer 1990;65:2811–7. - PubMed
    1. Gibson G, Ahmed I. Perianal and genital basal cell carcinoma: a clinicopathologic review of 51 cases. J Am Acad Dermatol 2001;45:68–71. - PubMed
    1. Damin D, Rosito M, Gus P, Tarta C, Weindorfer M, Burger M, et al. . Perianal basal cell carcinoma. J Cutaneous Med Surg 2002;6:26–8. - PubMed

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