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Review
. 2020 Aug;38(3):697-710.
doi: 10.1016/j.ncl.2020.03.014.

Differential Diagnoses of Inclusion Body Myositis

Vinojini Vivekanandam  1 , Enrico Bugiardini  1 , Ashirwad Merve  2 , Matthew Parton  3 , Jasper M Morrow  1 , Michael G Hanna  3 , Pedro M Machado  4
Affiliations
Review

Differential Diagnoses of Inclusion Body Myositis

Vinojini Vivekanandam et al. Neurol Clin. 2020 Aug.

Abstract

Inclusion body myositis is a slowly progressive myopathy, characteristically affecting quadriceps and long finger flexors. Atypical presentations do occur, however, and there is overlap with other myopathies, including inflammatory and hereditary etiologies. This article discusses atypical cases and differential diagnoses and considers the role of imaging and histopathology in differentiating inclusion body myositis.

Keywords: Diagnosis; Inclusion body myositis; Inflammatory myopathy; Magnetic resonance imaging; Muscle biopsy; Muscular dystrophy.

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Conflict of interest statement

Disclosure P.M. Machado has received consulting/speaker’s fees from Abbvie, BMS, Celgene, Eli Lilly, Janssen, MSD, Novartis, Pfizer, Roche, and UCB.

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