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Comment
. 2020 Sep;19(9):588.
doi: 10.1038/d41573-020-00133-w.

Blocking GDF15 signalling reverses cachexia

Comment

Blocking GDF15 signalling reverses cachexia

Sarah Crunkhorn. Nat Rev Drug Discov. 2020 Sep.
No abstract available

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Comment on

  • Antibody-mediated inhibition of GDF15-GFRAL activity reverses cancer cachexia in mice.
    Suriben R, Chen M, Higbee J, Oeffinger J, Ventura R, Li B, Mondal K, Gao Z, Ayupova D, Taskar P, Li D, Starck SR, Chen HH, McEntee M, Katewa SD, Phung V, Wang M, Kekatpure A, Lakshminarasimhan D, White A, Olland A, Haldankar R, Solloway MJ, Hsu JY, Wang Y, Tang J, Lindhout DA, Allan BB. Suriben R, et al. Nat Med. 2020 Aug;26(8):1264-1270. doi: 10.1038/s41591-020-0945-x. Epub 2020 Jul 13. Nat Med. 2020. PMID: 32661391

References

    1. Suriben, R. et al. Antibody-mediated inhibition of GDF15–GFRAL activity reverses cancer cachexia in mice Nat. Med. https://doi.org/10.1038/s41591-020-0945-x (2020)

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