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Review
. 2020 Oct;55(10):2547-2555.
doi: 10.1002/ppul.24978. Epub 2020 Jul 30.

Children and COVID-19: Microbiological and immunological insights

Danilo Buonsenso  1   2 , Michela Sali  1   3 , Davide Pata  4 , Cristina De Rose  4 , Maurizio Sanguinetti  1   3 , Piero Valentini  2   4 , Giovanni Delogu  1   5
Affiliations
Review

Children and COVID-19: Microbiological and immunological insights

Danilo Buonsenso et al. Pediatr Pulmonol. 2020 Oct.

Abstract

Since its first description in China, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread worldwide being declared a pandemic by the World Health Organization. More than 10.3 million people have been infected and more than 506 000 people died. However, SARS-CoV-2 had a lower impact on the pediatric population. Only about 1% to 2% of infected people are children and few deaths under the age of 14 are described so far. In this article, we discuss microbiological and immunological characteristics of SARS-CoV-2 infection in children highlighting the main differences from adult SARS-CoV-2 infection.

Keywords: COVID-19; SARS-CoV-2; children; immunology; novel coronavirus.

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References

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