Oral cancer and ACE2 receptor of SARS-CoV-2

Hercílio Martelli-Júnior¹, Renato Assis Machado², Daniella Reis Barbosa Martelli³, Mariléia Chaves Andrade⁴, Ricardo D Coletta⁵

Affiliations

¹ Oral Diagnosis, Dental School, State University of Montes Claros, Unimontes, Montes Claros, Minas Gerais, Brazil; Center for Rehabilitation of Craniofacial Anomalies, Dental School, University of Alfenas, Minas Gerais, Brazil.
² Hospital for Rehabilitation of Craniofacial Anomalies, University of São Paulo (HRAC/USP), Bauru, São Paulo, Brazil; Department of Oral Diagnosis, School of Dentistry, University of Campinas, FOP-UNICAMP, Piracicaba, São Paulo, Brazil. Electronic address: renatoassismachado@yahoo.com.br.
³ Oral Diagnosis, Dental School, State University of Montes Claros, Unimontes, Montes Claros, Minas Gerais, Brazil.
⁴ Department of Pathophysiology, State University of Montes Claros, Unimontes, Montes Claros, Minas Gerais, Brazil.
⁵ Department of Oral Diagnosis, School of Dentistry, University of Campinas, FOP-UNICAMP, Piracicaba, São Paulo, Brazil.

PMID: 32713810
PMCID: PMC7373056
DOI: 10.1016/j.oraloncology.2020.104920

Comment

Oral cancer and ACE2 receptor of SARS-CoV-2

Hercílio Martelli-Júnior et al. Oral Oncol. 2020 Sep.

. 2020 Sep:108:104920.

doi: 10.1016/j.oraloncology.2020.104920. Epub 2020 Jul 21.

Authors

Hercílio Martelli-Júnior¹, Renato Assis Machado², Daniella Reis Barbosa Martelli³, Mariléia Chaves Andrade⁴, Ricardo D Coletta⁵

Affiliations

¹ Oral Diagnosis, Dental School, State University of Montes Claros, Unimontes, Montes Claros, Minas Gerais, Brazil; Center for Rehabilitation of Craniofacial Anomalies, Dental School, University of Alfenas, Minas Gerais, Brazil.
² Hospital for Rehabilitation of Craniofacial Anomalies, University of São Paulo (HRAC/USP), Bauru, São Paulo, Brazil; Department of Oral Diagnosis, School of Dentistry, University of Campinas, FOP-UNICAMP, Piracicaba, São Paulo, Brazil. Electronic address: renatoassismachado@yahoo.com.br.
³ Oral Diagnosis, Dental School, State University of Montes Claros, Unimontes, Montes Claros, Minas Gerais, Brazil.
⁴ Department of Pathophysiology, State University of Montes Claros, Unimontes, Montes Claros, Minas Gerais, Brazil.
⁵ Department of Oral Diagnosis, School of Dentistry, University of Campinas, FOP-UNICAMP, Piracicaba, São Paulo, Brazil.

PMID: 32713810
PMCID: PMC7373056
DOI: 10.1016/j.oraloncology.2020.104920

No abstract available

Keywords: COVID-19; Oral squamous cell carcinoma; Renin-angiotensin system.

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Conflict of interest statement

Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Comment on

Tobacco Smoking Increases the Lung Gene Expression of ACE2, the Receptor of SARS-CoV-2.
Cai G, Bossé Y, Xiao F, Kheradmand F, Amos CI. Cai G, et al. Am J Respir Crit Care Med. 2020 Jun 15;201(12):1557-1559. doi: 10.1164/rccm.202003-0693LE. Am J Respir Crit Care Med. 2020. PMID: 32329629 Free PMC article. No abstract available.

References

1. Vieira A. Oral manifestations in Coronavirus disease 2019 (COVID-19) Oral Disease. 2020 (in press) - PMC - PubMed
1. Carrillo-Larco R.M., Altez-Fernandez C. Anosmia and dysgeusia in COVID-19: a systematic review. Wellcome Open Res. 2020;2020(5):94. - PMC - PubMed
1. Xu H., Zhong L., Deng J., Peng J., Dan H., Zeng X. High expression of ACE2 receptor of 2019-nCoV on the epithelial cells of oral mucosa. Int J Oral Sci. 2020;12:8. - PMC - PubMed
1. Hsu P.J., Yan K., Shi H., Izumchenko E., Agrawal N. Molecular biology of oral cavity squamous cell carcinoma. Oral Oncol. 2020;102 - PMC - PubMed
1. Fraga C.A.C., Farias L.C., Jones K.M., Paula A.M.B., Guimarães A.L.S. Angiotensin-converting enzymes (ACE and ACE2) as potential targets for malignant epithelial neoplasia: review and bioinformatics analyses focused in oral squamous cell carcinoma. Protein Pept Lett. 2017;24(9):1–9. - PubMed

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Oral cancer and ACE2 receptor of SARS-CoV-2

Affiliations

Oral cancer and ACE2 receptor of SARS-CoV-2

Authors

Affiliations

Conflict of interest statement

Comment on

References

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MeSH terms

Substances

LinkOut - more resources

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Medical

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