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Review
. 2020 Jul 20;6(7):e04508.
doi: 10.1016/j.heliyon.2020.e04508. eCollection 2020 Jul.

Green synthesis of copper oxide nanoparticles for biomedical application and environmental remediation

Sunday Adewale Akintelu  1   2 , Aderonke Similoluwa Folorunso  3 , Femi Adekunle Folorunso  4 , Abel Kolawole Oyebamiji  2   5
Affiliations
Review

Green synthesis of copper oxide nanoparticles for biomedical application and environmental remediation

Sunday Adewale Akintelu et al. Heliyon. .

Abstract

Recent development in nanoscience and nanotechnology has contributed to the wide applications of metal and metal oxides nanoparticles in several field of sciences, research institutes and industries. Among all metal oxides, copper oxide nanoparticles (CuONPs) has gained more attention due to its distinctive properties and applications. The high cost of reagents, equipment and environmental hazards associated with the physical and chemical methods of synthesizing CuONPs has been a major setback. In order to puffer solution to the aforementioned challenges by reducing environmental pollution and production of cheaper nanoparticles with good properties and efficiency, this review focus on collection of comprehensive information from recent developments in the synthesis, characterization and applications from previous scientific findings on biological method of synthesizing CuONPs due to the acclaimed advantages of been cheap, environmentally friendly, convenient and possibility of been scale up in into large scale production reported by numerous researchers. Our finding also support the synthesis of CuONPs from plant sources due to relative abundance of plants for the production of reducing and stabilizing agents required for CuONPs synthesis, potential efficiency of plant biomolecules in enhancing the toxicity effect of CuONPs against microbes, prevention of environmental pollution due of nontoxic chemicals and degradation effectiveness of CuONPs synthesized from plant sources. Furthermore, this study provide useful information on the rapid synthesis of CuONPs with desired properties from plant extracts.

Keywords: Applications; Characterization; Copper oxide nanoparticles; Inorganic chemistry; Plants extracts; Synthesis.

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Figures

Figure 1
Figure 1
Flow chat representing the various methods of synthesis of CuONPs
Figure 2
Figure 2
Flow chart showing some applications of CuONPs.
Figure 3
Figure 3
Probable mechanism of CuONPs toxicity against bacteria.
Figure 4
Figure 4
The probable mechanisms of CuONPs induced cytotoxicity in cancer cell lines.
Figure 5
Figure 5
A schematic representation of degradation of some pollutants using the CuONPs.
See this image and copyright information in PMC

References

    1. Folorunso A., Akintelu S., Oyebamiji A.K., Ajayi S., Abiola B., Abdusalam I., Morakinyo A. Biosynthesis, characterization and antimicrobial Activity of gold nanoparticles from leaf extracts of Annona muricata. J. Nanostr. Chem. 2019;9(2):111–117.
    1. Akintelu S.A., Folorunso A.S., Ademosun O.T. Instrumental characterization and antibacterial investigation of silver nanoparticles synthesized from Garcinia kola leaf. J. Drug Deliv. Therapeut. 2019;9(6-s):58–64.
    1. Akintelu S.A., Folorunso A.S. Biosynthesis, characterization and antifungal investigation of Ag-Cu nanoparticles from bark extracts of Garcina kola. Stem Cell. 2019;10(4):30–37.
    1. Akintelu S.A., Folorunso A.S., Oyebamiji A.K., Erazua E.A. Antibacterial potency of silver nanoparticles synthesized using Boerhaavia diffusa leaf extract as reductive and stabilizing agent. Int. J. Pharma Sci. Res. 2019;10(12):374–380.
    1. Khatereh P., Heshmatollah A., Mahmoud N. Green synthesis of Ni@Fe3O4 and CuO nanoparticles using Euphorbia maculata extract as photocatalysts for the degradation of organic pollutants under UV-irradiation. Ceram. Int. 2019;45:17173–17182.

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