Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Editorial
. 2020 Nov 15;202(10):1336-1337.
doi: 10.1164/rccm.202006-2456ED.

Spelunking in Sputum: Single-Cell RNA Sequencing Sheds New Insights into Cystic Fibrosis

Naoki Iwanaga  1 , Jay K Kolls  1
Affiliations
Editorial

Spelunking in Sputum: Single-Cell RNA Sequencing Sheds New Insights into Cystic Fibrosis

Naoki Iwanaga et al. Am J Respir Crit Care Med. .
No abstract available

PubMed Disclaimer

Comment on

  • Single-Cell Transcriptional Archetypes of Airway Inflammation in Cystic Fibrosis.
    Schupp JC, Khanal S, Gomez JL, Sauler M, Adams TS, Chupp GL, Yan X, Poli S, Zhao Y, Montgomery RR, Rosas IO, Dela Cruz CS, Bruscia EM, Egan ME, Kaminski N, Britto CJ. Schupp JC, et al. Am J Respir Crit Care Med. 2020 Nov 15;202(10):1419-1429. doi: 10.1164/rccm.202004-0991OC. Am J Respir Crit Care Med. 2020. PMID: 32603604 Free PMC article.

References

    1. Riordan JR, Rommens JM, Kerem B, Alon N, Rozmahel R, Grzelczak Z, et al. Identification of the cystic fibrosis gene: cloning and characterization of complementary DNA. Science. 1989;245:1066–1073. - PubMed
    1. Elborn JS. Cystic fibrosis. Lancet. 2016;388:2519–2531. - PubMed
    1. Stoltz DA, Meyerholz DK, Welsh MJ. Origins of cystic fibrosis lung disease. N Engl J Med. 2015;372:351–362. - PMC - PubMed
    1. Shanthikumar S, Burton M, Saffery R, Ranganathan SC, Neeland MR. Single-cell flow cytometry profiling of BAL in children. Am J Respir Cell Mol Biol. 2020;63:152–159. - PubMed
    1. Kormann MSD, Dewerth A, Eichner F, Baskaran P, Hector A, Regamey N, et al. Transcriptomic profile of cystic fibrosis patients identifies type I interferon response and ribosomal stalk proteins as potential modifiers of disease severity. PLoS One. 2017;12:e0183526. - PMC - PubMed