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. 2020 Jul 24;8(3):230.
doi: 10.3390/healthcare8030230.

Can Simple Tests Prior to Endoscopy Predict the OLGA Stage of Gastritis?

Ertan Bulbuloglu  1 , Hasan Dagmura  2 , Emin Daldal  3 , Alev Deresoy  4 , Huseyin Bakir  5 , Ugur Ozsoy  6 , Ali Ihsan Saglam  6 , Osman Demir  7
Affiliations

Can Simple Tests Prior to Endoscopy Predict the OLGA Stage of Gastritis?

Ertan Bulbuloglu et al. Healthcare (Basel). .

Abstract

Gastritis is a progressive disease that evolves from a non-atrophic to atrophic state and progresses through intestinal metaplasia, with some cases leading eventually to gastric cancer. Since gastritis by definition is an inflammatory process of the mucosal lining of the stomach and is usually associated with pain, we aimed to identify any association between the severity of gastritis and pain and a simple inflammatory marker derived from a complete blood count (CBC). This was a prospective cross-sectional study which enrolled 155 consecutive adult patients who underwent an upper endoscopy. Prior to the endoscopy, all patients were given a questionnaire, numerical rating scale (NRS) and complete blood count evaluation. The biopsy was obtained from the gastric mucosa according to the modified Sydney classification and scored with the Operative Link for Gastritis Assessment (OLGA) scoring system. The results showed a significant correlation between NRS and intestinal metaplasia (p < 0.01); moreover, a correlation was also found between the NRS and OLGA stage (r = 0.469, p < 0.001). A nonlinear curve was constructed for OLGA stage estimation according to NRS scores (r2 was found to be 0.442, with p < 0.001). The results also showed a correlation between the neutrophil to the lymphocyte ratio (NLR) and OLGA stage (p < 0.01). No correlation was found between the other gastric parameters and NLR (p > 0.05). Helicobacter pylori positivity did not correlate with NRS and NLR. As a conclusion, pain measured by NRS and NLR, which are simply calculated from the CBC prior to endoscopy, may be used to predict OLGA stages and estimate the severity of gastritis in endoscopy patients.

Keywords: Operative Link for Gastritis Assessment; endoscopy; gastric cancer; neutrophil to lymphocyte ratio; numerical rating scale; pain.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Flowchart of the selection of the study group patients.
Figure 2
Figure 2
Curve estimations between numerical rating scale (NRS) and Operative Link for Gastritis Assessment (OLGA) stage (OLGA = 1.907 − 0.434 ∗ NRS + 0.065 ∗ NRS2).
Figure 3
Figure 3
Comparison of the OLGA stage according to the neutrophil to lymphocyte ratio (NLR) and the NRS groups (n = 14, n = 141).
See this image and copyright information in PMC

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