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Randomized Controlled Trial
. 2020 Jul 28;21(1):682.
doi: 10.1186/s13063-020-04610-w.

Manual therapy versus therapeutic exercise in non-specific chronic neck pain: a randomized controlled trial

Carlos Bernal-Utrera  1   2 , Juan Jose Gonzalez-Gerez  3   4 , Ernesto Anarte-Lazo  5   6 , Cleofas Rodriguez-Blanco  3   7
Affiliations
Randomized Controlled Trial

Manual therapy versus therapeutic exercise in non-specific chronic neck pain: a randomized controlled trial

Carlos Bernal-Utrera et al. Trials. .

Abstract

Background: Nonspecific chronic neck pain is a fairly common disorder that causes a great impact, and it is greatly influenced by psychosocial factors. Among a number of treatment modalities described for its management, the most common approach is based on manual therapy and specific therapeutic exercise, which have shown a moderate effect on subjects with chronic non-specific neck pain. However, the effect times of these treatments have not been accurately detailed. Our study aims to break down and compare the effects of two experimental treatments based on manual therapy and therapeutic exercise.

Methods: The short-term and mid-term changes produced by different therapies on subjects with non-specific chronic neck pain were studied. The sample was randomized divided into three groups: manual therapy, therapeutic exercise, and placebo. As dependent variables of our research, we studied (a) pain, based on the visual analog scale and the pressure pain threshold, and (b) cervical disability, through the Neck Disability Index (NDI). Outcomes were registered on week 1, week 4, and week 12. The findings were analyzed statistically considering a 5% significance level (P ≤ 0.05).

Results: No statistically significant differences (P 0.05) were obtained between the experimental groups, if they exist against the control group. Nonetheless, we found that manual therapy improved perceived pain before than therapeutic exercise, while therapeutic exercise reduced cervical disability before than manual therapy. Effect size (R2) shows medium and large effects for both experimental treatments.

Conclusion: There are no differences between groups in short and medium terms. Manual therapy achieves a faster reduction in pain perception than therapeutic exercise. Therapeutic exercise reduces disability faster than manual therapy. Clinical improvement could potentially be influenced by central processes.

Trial registration: Brazilian Clinical Trial Registry, RBR-2vj7sw. Registered on 28 November 2018.

Keywords: Chronic pain; Exercise therapy; Musculoskeletal manipulations; Neck pain; Physical therapy specialty; Randomized controlled trial.

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Conflict of interest statement

The authors declare that they have not competing interests.

Figures

Fig. 1
Fig. 1
CONSORT flow diagram
See this image and copyright information in PMC

References

    1. Childs JD, Cleland JA, Elliott JM, Teyhen DS, Wainner RS, Whitman JM, et al. Neck pain: clinical practice guidelines linked to the International Classification of Functioning, Disability, and Health from the Orthopedic Section of the American Physical Therapy Association. J Orthop Sports Phys Ther. 2008;38(9):1e34. - PubMed
    1. Cohen SP. Epidemiology, diagnosis, and treatment of neck pain. Mayo Clin Proc England. 2015;90(2):284–299. - PubMed
    1. Daffner SD, Hilibrand AS, Hanscom BS, Brislin BT, Vaccaro AR, Albert TJ. Impact of neck and arm pain on overall health status. Spine (Phila Pa 1976) 2003;28(17):2030–2035. - PubMed
    1. Safiri S, Kolahi AA, Hoy D, Buchbinder R, Mansournia MA, Bettampadi D, Ashrafi-Asgarabad A, Almasi-Hashiani A, Smith E, Sepidarkish M, Cross M, Qorbani M, Moradi-Lakeh M, Woolf AD, March L, Collins G, Ferreira ML. Global, regional, and national burden of neck pain in the general population, 1990-2017: systematic analysis of the Global Burden of Disease Study 2017. BMJ (Clinical research ed) 2020;368:m791. - PMC - PubMed
    1. Treleaven J. Sensorimotor disturbances in neck disorders affecting postural stability, head and eye movement control. Man Ther. 2008;13(1):2–11. - PubMed

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