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Case Reports
. 2020 Sep;16(9):1372-1375.
doi: 10.1016/j.soard.2020.06.011. Epub 2020 Jul 9.

Colorectal surgery obesity-related morbidity during COVID-19

Lisandro Montorfano  1 , Rafael Miret  1 , Asad Ur Rahman  2 , Mileydis Alonso  1 , David J Maron  3 , Mayank Roy  1 , Francisco Ferri  1 , Pablo Bejarano  4 , Steven D Wexner  5
Affiliations
Case Reports

Colorectal surgery obesity-related morbidity during COVID-19

Lisandro Montorfano et al. Surg Obes Relat Dis. 2020 Sep.

Abstract

Tocilizumab, a monoclonal antiinterluekin-6 receptor antibody, has been empirically used in the treatment of cytokine release syndrome associated with severe coronavirus disease 2019 infections. The efficacy and safety of these medications for these patients is unknown. The purpose of this report was to present a case of acute large bowel perforation in a morbidly obese patient with coronavirus disease 2019 pneumonia who received empiric Tocilizumab. This case report analyzes the risks of acute large bowel perforation after using this medication empirically and discusses the appropriate management of this adverse event.

Keywords: Bowel perforation; COVID-19; Colonic perforation; Corticosteroids; IL-6; SARS-CoV-2 coronavirus; Tocilizumab.

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Figures

Fig. 1
Fig. 1
Chest X-ray with multispace air opacities.
Fig. 2
Fig. 2
Chest X-ray demonstrating pneumoperitoneum.
Fig. 3
Fig. 3
Transmural coagulative necrosis involving the cecum and extensive fibrinopurulent serositis.
See this image and copyright information in PMC

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