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Case Reports
. 2020 Apr 29:9:310.
doi: 10.12688/f1000research.23204.2. eCollection 2020.

Appearance and management of COVID-19 laryngo-tracheitis: two case reports

Affiliations
Case Reports

Appearance and management of COVID-19 laryngo-tracheitis: two case reports

Charles Matthew Oliver et al. F1000Res. .

Abstract

We present two cases of coronavirus disease 2019 (COVID-19)-related laryngotracheitis in good-prognosis, ventilated patients who had failed extubation. As the pandemic continues to unfold across the globe and better management of those with respiratory failure develops, this may be an increasingly common scenario. Close ENT-intensivist liaison, meticulous team preparation, early consideration of rigid endoscopy and prospective data collection and case sharing are recommended.

Keywords: Airway management; COVID; Intensive care; SARS-CoV-19.

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Conflict of interest statement

No competing interests were disclosed.

Figures

Figure 1.
Figure 1.. Case 1 radiographs.
( A) Post-intubation plain chest radiograph, on ICU on day 5 post-onset of symptoms. ( B) Plain chest radiograph on day 10 post-onset of symptoms.
Figure 2.
Figure 2.. Case 1 glottis images.
( A) View of supraglottis showing ulcerated epiglottis. ( B) Glottis showing relative sparing of vocal cords and false cords, but profound subglottic oedema. ( C) Following change to size 6 endotracheal tube, there is some anterior glottic airway. ( D) However, the subglottis is also ulcerated and oedematous mucosa prevents rigid bronchoscopy (0 o Hopkins’ rod) beyond the third tracheal ring. White arrows indicate areas of ulceration and red arrow subglottic oedema.
Figure 3.
Figure 3.. Case 2 radiographs.
( A) Post-intubation plain chest radiograph, on day 1 of hospital admission. ( B) Day 5 following re-intubation.
Figure 4.
Figure 4.. Case 2 glottis images.
( A) View of supraglottis showing ulcerated glottis. ( B) Glottis showing sparing of false cords, but profound glottic oedema and glottic and subglottic ulceration. ( C) Flexible bronchoscopy via the anterior commissure shows subglottic oedema and granulation tissue (black arrow). ( D) Oedematous mucosa prevents flexible bronchoscopy beyond the third tracheal ring. White arrows indicate areas of ulceration, black arrow granulation tissue and red arrow tracheal oedema.

References

    1. Huang C, Wang Y, Li X, et al. : Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet. 2020;395(10223):497–506. 10.1016/S0140-6736(20)30183-5 - DOI - PMC - PubMed
    1. Guan WJ, Ni ZY, Hu Y, et al. : Clinical Characteristics of Coronavirus Disease 2019 in China. N Engl J Med. 2020; NEJMoa2002032. 10.1056/NEJMoa2002032 - DOI - PMC - PubMed
    1. Davenport L: ICU Lessons on COVID-19 From Italian Front Line: Be Flexible.2020; (accessed 29.03.20 2020). Reference Source
    1. Royal College of Anaesthetists: Royal College of Anaesthetists COVID-19 clinical guidance.2020; (accessed 29.03.20 2020). Reference Source
    1. Cormack RS, Lehane J: Difficult tracheal intubation in obstetrics. Anaesthesia. 1984;39(11):1105–11. 10.1111/j.1365-2044.1984.tb08932.x - DOI - PubMed

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