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Review
. 2020 Nov;382(2):267-279.
doi: 10.1007/s00441-020-03255-0. Epub 2020 Jul 28.

Neuro-regenerative potential of dental stem cells: a concise review

Duaa Abuarqoub  1   2 , Nazneen Aslam  3 , Bayan Almajali  4 , Leen Shajrawi  4 , Hanan Jafar  3   4 , Abdalla Awidi  5   6
Affiliations
Review

Neuro-regenerative potential of dental stem cells: a concise review

Duaa Abuarqoub et al. Cell Tissue Res. 2020 Nov.

Abstract

This review will summarize the research information regarding the regenerative potential of dental stem cells for the treatment of neurodegenerative disorders. As compared to existing treatment modalities, the stem cell therapy seems promising, and accumulating evidences about the differentiation of stem cells into various lineages are proving it. The incidence of neurodegenerative diseases such as Alzheimer's, Parkinson's, stroke, and peripheral neuropathy is increasing due to the rise in life expectancies of people which have put a huge burden on economies. Finding a promising treatment could benefit not only the patients but also the communities. Dental stem cells hold a great potential to differentiate into neuronal cells. Many studies have reported the differentiation potential of the dental stem cells with the presence of neuronal lineage markers. In this review, we conferred how the use of dental stem cells can benefit the above-mentioned bedridden diseases.

Keywords: Dental; Differentiation; Neuro-degenerative disorders; Neuro-regeneration; Stem cells.

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