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Comment
. 2021 Mar 1;113(3):223-224.
doi: 10.1093/jnci/djaa098.

Identifying the Radioresponsive Genome for Genomics-Guided Radiotherapy

Catharine M L West  1
Affiliations
Comment

Identifying the Radioresponsive Genome for Genomics-Guided Radiotherapy

Catharine M L West. J Natl Cancer Inst. .
No abstract available

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Comment on

  • Pathogenic ATM Mutations in Cancer and a Genetic Basis for Radiotherapeutic Efficacy.
    Pitter KL, Casey DL, Lu YC, Hannum M, Zhang Z, Song X, Pecorari I, McMillan B, Ma J, Samstein RM, Pei IX, Khan AJ, Braunstein LZ, Morris LGT, Barker CA, Rimner A, Alektiar KM, Romesser PB, Crane CH, Yahalom J, Zelefsky MJ, Scher HI, Bernstein JL, Mandelker DL, Weigelt B, Reis-Filho JS, Lee NY, Powell SN, Chan TA, Riaz N, Setton J. Pitter KL, et al. J Natl Cancer Inst. 2021 Mar 1;113(3):266-273. doi: 10.1093/jnci/djaa095. J Natl Cancer Inst. 2021. PMID: 32726432 Free PMC article.

References

    1. Pitter KL, Casey DL, Lu YC, et al. Pathogenic ATM mutations in cancer and a genetic basis for 2 radiotherapeutic efficacy. J Natl Cancer Inst. 2021;113(3):266–273. - PMC - PubMed
    1. Savitsky K, Bar-Shira A, Gilad S, Rotman G, et al. A single ataxia telangiectasia gene with a product similar to PI-3 kinase. Science. 1995;268(5218):1749–1753. - PubMed
    1. Andreassen CN, Rosenstein BS, Kerns SL, et al. International Radiogenomics Consortium (RgC). Individual patient data meta-analysis shows a significant association between the ATM rs1801516 SNP and toxicity after radiotherapy in 5456 breast and prostate cancer patients. Radiother Oncol. 2016;121(3):431–439. - PMC - PubMed
    1. DeWire MD, Beltran C, Boop FA, et al. Radiation therapy and adjuvant chemotherapy in a patient with a malignant glioneuronal tumor and underlying ataxia telangiectasia: a case report and review of the literature. J Clin Oncol. 2013;31(1):e12. - PMC - PubMed
    1. Ma J, Setton J, Morris L, et al. Genomic analysis of exceptional responders to radiotherapy reveals somatic mutations in ATM. Oncotarget. 2017;8(6):10312–10323. - PMC - PubMed

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