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Comment
. 2020 Jul 29;5(1):136.
doi: 10.1038/s41392-020-00244-1.

Microbiome harbored within tumors: a new chance to revisit our understanding of cancer pathogenesis and treatment

Kunming Zhao  1   2 , Ying Hu  3   4
Affiliations
Comment

Microbiome harbored within tumors: a new chance to revisit our understanding of cancer pathogenesis and treatment

Kunming Zhao et al. Signal Transduct Target Ther. .
No abstract available

PubMed Disclaimer

Conflict of interest statement

The authors declare no competing interests.

Figures

Fig. 1
Fig. 1
Microbiome in tumors may be actively involved in microenvironment reconstruction and then play roles in the cancer pathogenesis and treatment response
See this image and copyright information in PMC

Comment on

  • The human tumor microbiome is composed of tumor type-specific intracellular bacteria.
    Nejman D, Livyatan I, Fuks G, Gavert N, Zwang Y, Geller LT, Rotter-Maskowitz A, Weiser R, Mallel G, Gigi E, Meltser A, Douglas GM, Kamer I, Gopalakrishnan V, Dadosh T, Levin-Zaidman S, Avnet S, Atlan T, Cooper ZA, Arora R, Cogdill AP, Khan MAW, Ologun G, Bussi Y, Weinberger A, Lotan-Pompan M, Golani O, Perry G, Rokah M, Bahar-Shany K, Rozeman EA, Blank CU, Ronai A, Shaoul R, Amit A, Dorfman T, Kremer R, Cohen ZR, Harnof S, Siegal T, Yehuda-Shnaidman E, Gal-Yam EN, Shapira H, Baldini N, Langille MGI, Ben-Nun A, Kaufman B, Nissan A, Golan T, Dadiani M, Levanon K, Bar J, Yust-Katz S, Barshack I, Peeper DS, Raz DJ, Segal E, Wargo JA, Sandbank J, Shental N, Straussman R. Nejman D, et al. Science. 2020 May 29;368(6494):973-980. doi: 10.1126/science.aay9189. Science. 2020. PMID: 32467386 Free PMC article.

References

    1. Nejmen D, et al. The human tumor microbiome is composed of tumor type–specific intracellular bacteria. Science. 2020;368:973–980. doi: 10.1126/science.aay9189. - DOI - PMC - PubMed
    1. Junttila MR, et al. Influence of tumour micro-environment heterogeneity on therapeutic response. Nature. 2013;501:346–354. doi: 10.1038/nature12626. - DOI - PubMed
    1. Łaniewski P, et al. The microbiome and gynaecological cancer development, prevention and therapy. Nat. Rev. Urol. 2020;17:232–250. doi: 10.1038/s41585-020-0286-z. - DOI - PMC - PubMed
    1. Riquelme E, et al. Tumor microbiome diversity and composition influence pancreatic cancer outcomes. Cell. 2019;178:795–806. doi: 10.1016/j.cell.2019.07.008. - DOI - PMC - PubMed
    1. Gopalakrishnan V, et al. The influence of the gut microbiome on cancer, immunity, and cancer immunotherapy. Cancer Cell. 2018;33:570–580. doi: 10.1016/j.ccell.2018.03.015. - DOI - PMC - PubMed

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