The other side of the innate immune system: humoral arms favoring cancer
- PMID: 32728201
- PMCID: PMC7609556
- DOI: 10.1038/s41423-020-0512-x
The other side of the innate immune system: humoral arms favoring cancer
Abstract
Cancer cells take advantage of NETosis to escape host immune surveillance and mediate metastasis. The pharmacological targeting of NETosis may prove beneficial in maximizing the response to cancer immunotherapy.
Conflict of interest statement
The authors declare no competing interests.
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CXCR1 and CXCR2 Chemokine Receptor Agonists Produced by Tumors Induce Neutrophil Extracellular Traps that Interfere with Immune Cytotoxicity.Immunity. 2020 May 19;52(5):856-871.e8. doi: 10.1016/j.immuni.2020.03.001. Epub 2020 Apr 13. Immunity. 2020. PMID: 32289253
References
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- Jaillon, S. et al. Neutrophil diversity and plasticity in tumour progression and therapy. Nat. Rev. Cancer. 2020. In press. 10.1038/s41568-020-0281-y. - PubMed
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