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. 2020 Jul 23:2020:10.17912/micropub.biology.000282.
doi: 10.17912/micropub.biology.000282.

The teratogenic effect of Triclosan on embryogenesis is attenuated by Tween 20 in Caenorhabditis elegans

Youngyong Park #  1 , Matthew A Gaddy #  1 , Mohammad A Alfhili  2 , Myon Hee Lee  1
Affiliations

The teratogenic effect of Triclosan on embryogenesis is attenuated by Tween 20 in Caenorhabditis elegans

Youngyong Park et al. MicroPubl Biol. .
No abstract available

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Figures

Figure 1. TCS-induced embryo shrinkage and mortality is abolished by Tween 20
Figure 1. TCS-induced embryo shrinkage and mortality is abolished by Tween 20
(A) Molecular structure of TCS. (B) Hatching rate of wild-type (N2) embryos at varying TCS concentrations in the presence and absence of Tween 20 (Tw20). ***, p<0.001; ns, not significant. (C-E) DAPI staining. (C) N2 embryos (~250-cell stage; a midstage embryo just before morphogenesis) and subsequent hatching visualized with DAPI (pink). (D) N2 embryos exposed to TCS show shrinkage of inner cell mass and mortality. Arrows indicate shrinkage. (E) Tw20 abrogates TCS-induced impaired hatching. Scale bar, 10 µm.
See this image and copyright information in PMC

References

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