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Review
. 2020 Oct;67(10):e28621.
doi: 10.1002/pbc.28621. Epub 2020 Jul 30.

Pediatric ovarian Sertoli-Leydig cell tumors with heterologous rhabdomyosarcoma elements: Clinical case series and review of the literature

Jane Koo  1 , Timothy P Garrington  1 , Karol Kerr  1 , Amy L Treece  2 , Carrye R Cost  1
Affiliations
Review

Pediatric ovarian Sertoli-Leydig cell tumors with heterologous rhabdomyosarcoma elements: Clinical case series and review of the literature

Jane Koo et al. Pediatr Blood Cancer. 2020 Oct.

Abstract

Sertoli-Leydig cell tumors (SLCTs) are rare ovarian neoplasms in pediatric patients. More exceedingly rare are SLCTs that also contain heterologous rhabdomyosarcoma (RMS) elements. For these patients, there is no standardized treatment. We report four cases of pediatric SLCT with heterologous RMS elements that were successfully treated with surgical resection and adjuvant chemotherapy. All four patients are alive and remain in remission.

Keywords: Sertoli-Leydig cell tumor; heterologous elements; rhabdomyosarcoma.

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References

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