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Observational Study
. 2020;51(8):669-674.
doi: 10.1159/000510259. Epub 2020 Jul 30.

COVID-19 in Hospitalized Patients on Chronic Peritoneal Dialysis: A Case Series

Mala Sachdeva  1 , Nupur N Uppal  2 , Jamie S Hirsch  2   3   4 , Jia H Ng  2 , Deepa Malieckal  2 , Steven Fishbane  2 , Kenar D Jhaveri  2 ; Northwell COVID-19 Research Consortium and the Northwell Nephrology COVID-19 Research Consortium
Collaborators, Affiliations
Observational Study

COVID-19 in Hospitalized Patients on Chronic Peritoneal Dialysis: A Case Series

Mala Sachdeva et al. Am J Nephrol. 2020.

Abstract

Background: The COVID-19 pandemic has affected the end-stage kidney disease (ESKD) population, with high mortality rates reported among patients on hemodialysis. However, the degree to which it has affected the peritoneal dialysis (PD) population in the United States has not yet been elucidated. In this report, we describe the clinical characteristics, presentations, clinical course, and outcomes of ESKD patients on PD hospitalized with COVID-19.

Methods: We describe the characteristics, presentation, and outcomes of adult ESKD patients on chronic PD hospitalized with CO-VID-19 in our 13 major hospitals in the NY health system using descriptive statistical analysis.

Results: Of 419 hospitalized patients with ESKD, 11 were on chronic PD therapy (2.6%). Among those 11, 3 patients required mechanical ventilation, 2 of whom died. Of the entire cohort, 9 of the 11 patients (82%) were discharged alive. While fever was a common presentation, more than half of our patients also presented with diarrhea. Interestingly, 3 patients were diagnosed with culture-negative peritonitis during their hospitalization. Seven patients reported positive SARS-CoV-2 exposure from a member of their household.

Conclusion: Hospitalized patients on PD with COVID-19 had a relatively mild course, and majority of them were discharged home.

Keywords: Coronavirus disease 2019; End-stage kidney disease; Nephrology; Peritoneal dialysis.

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Conflict of interest statement

K.D.J. is a consultant for Astex Pharmaceuticals and Natera.

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