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Review
. 2021 Mar;97(1145):175-179.
doi: 10.1136/postgradmedj-2020-138080. Epub 2020 Jul 30.

COVID-19 in patients with heart failure: the new and the old epidemic

Affiliations
Review

COVID-19 in patients with heart failure: the new and the old epidemic

Nicolò Sisti et al. Postgrad Med J. 2021 Mar.

Abstract

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has spread in nearly 200 countries in less than 4 months since its first identification; accordingly, the coronavirus disease 2019 (COVID 2019) has affirmed itself as a clinical challenge. The prevalence of pre-existing cardiovascular diseases in patients with COVID19 is high and this dreadful combination dictates poor prognosis along with the higher risk of intensive care mortality. In the setting of chronic heart failure, SARS-CoV-2 can be responsible for myocardial injury and acute decompensation through various mechanisms. Given the clinical and epidemiological complexity of COVID-19, patiens with heart failure may require particular care since the viral infection has been identified, considering an adequate re-evaluation of medical therapy and a careful monitoring during ventilation.

Keywords: CARDIOLOGY; Heart failure.

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Conflict of interest statement

Competing interests: None declared.

Figures

Figure 1
Figure 1
Findings suggestive of decompensation and variables to be considered in the management of patients with COVID-19 having a history of heart failure. CV, cardiovascular; COVID-19, coronavirus disease 2019; PEEP, pulmonary end-expiratory pressure; PV, pulmonary vein (Images by Reaper DZ on Pixabay and CDC on Unsplash).

References

    1. Guan W-J, Ni Z-Y, Hu Y, et al. China medical treatment expert group for COVID-19, clinical characteristics of coronavirus disease 2019 in China. N Engl J Med 2020;1–13.10.1056/NEJMoa2002032. - DOI - PMC - PubMed
    1. Ponikowski P, Voors AA, Anker SD, et al. ESC guidelines for the diagnosis and treatment of acute and chronic heart failure. Eur Heart J 2016;37:2129–2200m.10.1093/eurheartj/ehw128. - DOI - PubMed
    1. Shi S, Qin M, Shen B, et al. Association of cardiac injury with mortality in hospitalized patients with COVID-19 in Wuhan, China. JAMA Cardiol 2020;1–8.10.1001/jamacardio.2020.0950. - DOI - PMC - PubMed
    1. Zhou F, Yu T, Du R, et al. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study. Lancet 2020;6736:1–9.10.1016/s0140-6736(20)30566-3. - DOI - PMC - PubMed
    1. Huang C, Wang Y, Li X, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet 2020;395:497–506.10.1016/S0140-6736(20)30183-5. - DOI - PMC - PubMed

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