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Review
. 2020 Jul 23;50(3):119-124.

Use of Clozapine in the General Hospital

Feras Ali Mustafa  1
Affiliations
Review

Use of Clozapine in the General Hospital

Feras Ali Mustafa. Psychopharmacol Bull. .

Abstract

Patients with treatment-resistant schizophrenia receiving clozapine therapy are at risk of potentially serious complications in the general hospital setting, due to the complex pharmacokinetic and pharmacodynamic profile of clozapine. We summarize common clinical challenges that face clinicians who care for clozapine patients in the general hospital, and make recommendations based on the available literature and clinical experience. Early collaborative management between consultation-liaison psychiatry and other clinical teams in the general hospital is paramount to improve clinical outcomes and avoid serious complications in this patient group.

Keywords: clozapine; consultation-liaison psychiatry; general hospital; treatment-resistant schizophrenia.

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Conflict of interest statement

Disclosure The author has no conflicts of interest to declare.

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