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. 2020 Jul 14:2020:6031708.
doi: 10.1155/2020/6031708. eCollection 2020.

Regional Variation of Pancreatic Cancer Incidence in the Nile Delta Region of Egypt over a Twelve-Year Period

Christina Baum  1 , Amr S Soliman  2 , Heidi E Brown  1 , Ibrahim A Seifeldin  3 , Mohamed Ramadan  3 , Breanne Lott  4 , An Nguyen  5 , Ahmed El-Ghawalby  6 , Ahmed Hablas  3
Affiliations

Regional Variation of Pancreatic Cancer Incidence in the Nile Delta Region of Egypt over a Twelve-Year Period

Christina Baum et al. J Cancer Epidemiol. .

Abstract

Background: Pancreatic cancer is one of the deadliest forms of cancer, with incidence rates rising in many countries around the world. Geographic variation in pancreatic cancer incidence has not been studied extensively, especially in low- and middle-income countries. The aim of this study was to characterize the distribution of pancreatic cancer incidence in the central Nile Delta region of Egypt and to examine differences by urban and rural patient residence using the nation's only population-based cancer registry.

Methods: Utilizing the Gharbiah province population-based cancer registry, data were abstracted for 1,089 pancreatic cancer cases diagnosed over twelve years from 1999 to 2010. Age- and sex-specific incidence rates were calculated and compared for urban and rural areas of the eight districts of Gharbiah.

Results: Age-adjusted incidence of pancreatic cancer within Gharbiah varied considerably by urban/rural patient residence and by district. Incidence rates were 1.3 times higher in urban compared to rural areas (4.45 per 100,000 in urban areas and 3.43 per 100,000 in rural areas). The highest incidence rates were observed in urban centers of Kotour, El Santa, and Kafr El-Zayat districts (12.94, 8.32, and 7.89, respectively).

Conclusion: Incidence rates varied greatly by urban and rural areas and by district of residence in the Nile Delta region of Egypt. Future studies should examine potential environmental risk factors that may contribute to the geographic distribution of pancreatic cancer in this region.

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Conflict of interest statement

The authors declare that there is no conflict of interest regarding the publication of this article.

Figures

Figure 1
Figure 1
Map of pancreatic cancer incidence rates in urban and rural Gharbiah for males and females (1999-2010).
Figure 2
Figure 2
Age-specific pancreatic cancer incidence rates per 1,089 cases in the Gharbiah district of Egypt (1999-2010).
See this image and copyright information in PMC

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