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. 2020 Jul 17:7:2374289520935591.
doi: 10.1177/2374289520935591. eCollection 2020 Jan-Dec.

Educational Case: Babesiosis and Transfusion-Transmitted Infections

Maureen J Miller  1 , Lauren McVoy  2 , Amy Rapkiewicz  3
Affiliations

Educational Case: Babesiosis and Transfusion-Transmitted Infections

Maureen J Miller et al. Acad Pathol. .

Abstract

The following fictional case is intended as a learning tool within the Pathology Competencies for Medical Education (PCME), a set of national standards for teaching pathology. These are divided into three basic competencies: Disease Mechanisms and Processes, Organ System Pathology, and Diagnostic Medicine and Therapeutic Pathology. For additional information, and a full list of learning objectives for all three competencies, see http://journals.sagepub.com/doi/10.1177/2374289517715040.1.

Keywords: babesiosis; diagnostic medicine; malaria; microbiology; parasitology; pathology competencies; transfusion-transmitted infections.

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Conflict of interest statement

Declaration of Conflicting Interests: The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

Figures

Figure 1.
Figure 1.
Peripheral blood smear, thin region (Giemsa stain, ×1000). Black arrow, normal platelet. Red arrow, intraerythrocytic trophozoite of Babesia microti. Blue arrow, extraerythrocytic trophozoite of B microti.
Figure 2.
Figure 2.
Left: Babesia microti in peripheral blood smear. Several red blood cells (RBCs) with small, vacuolated trophozoites are present. Right: Plasmodium falciparum in peripheral blood smear. Several headphones forms (trophozoites with double chromatin dot) and marginal or applique forms (trophozoites at the periphery of the RBC, sometimes appearing to follow the curvature of the cell) are present.
See this image and copyright information in PMC

References

    1. Knollman-Ritschel BEC, Regula DP, Borowitz MJ, Conran R, Prystowsky MB. Pathology competencies for medical education and educational cases. Acad Pathol. 2017:4 doi:10.1177/2374289517715040 - PMC - PubMed
    1. Centers for Disease Control and Prevention (CDC). Global Health Division of Parasitic Diseases. TickNET. 2007. Accessed April 18, 2019 https://www.cdc.gov/ticknet/index.html - PubMed
    1. Centers for Disease Control and Prevention (CDC). Global Health Division of Parasitic Diseases. DPDx—Laboratory Identification of Parasites of Public Health Concern. Babesiosis. 2017. Accessed April 18, 2019 https://www.cdc.gov/dpdx/babesiosis/index.html
    1. Vannier E, Krause PJ. Human Babesiosis. N Engl J Med. 2012;366:2397–2407. - PubMed
    1. Vannier EG, Diuk-Wasser MA, Ben Mamoun C, Krause PJ. Babesiosis. Infect Dis Clin North Am. 2015;29:357–370. - PMC - PubMed