Update on the COVID-19-associated inflammatory syndrome in children and adolescents; paediatric inflammatory multisystem syndrome-temporally associated with SARS-CoV-2

Davinder Singh-Grewal^{1

2

3

4}, Ryan Lucas^{1

2}, Kristine McCarthy^{1

2}, Allen C Cheng^{5

6}, Nicholas Wood^{1

2}, Genevieve Ostring^{7

8}, Philip Britton^{1

2}, Nigel Crawford^{9

10

11}, David Burgner^{9

12

13

14}

Affiliations

¹ Department of Rheumatology, The Sydney Children's Hospitals Network, Sydney, New South Wales, Australia.
² Paediatrics and Child Health, The University of Sydney, Sydney, New South Wales, Australia.
³ School of Maternal and Child Health, University of New South Wales, Sydney, New South Wales, Australia.
⁴ Department of Paediatrics, John Hunter Children's Hospital, Newcastle, New South Wales, Australia.
⁵ Department of Infectious Diseases, Alfred Health, Melbourne, Victoria, Australia.
⁶ School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia.
⁷ Paediatric Rheumatology, Starship Children's Hospital, Auckland, New Zealand.
⁸ University of Auckland, Paediatrics Child and Youth Health, Auckland, New Zealand.
⁹ Infection and Immunity, Murdoch Children's Research Institute, Melbourne, Victoria, Australia.
¹⁰ Immunisation Service, Royal Children's Hospital, Melbourne, Victoria, Australia.
¹¹ University of Melbourne, Melbourne, Victoria, Australia.
¹² Infectious Diseases University, Royal Children's Hospital, Melbourne, Victoria, Australia.
¹³ Department of Paediatrics, University of Melbourne, Melbourne, Victoria, Australia.
¹⁴ Department of Paediatrics, Monash University, Melbourne, Victoria, Australia.

PMID: 32735721
PMCID: PMC7436879
DOI: 10.1111/jpc.15049

Comment

Update on the COVID-19-associated inflammatory syndrome in children and adolescents; paediatric inflammatory multisystem syndrome-temporally associated with SARS-CoV-2

Davinder Singh-Grewal et al. J Paediatr Child Health. 2020 Aug.

. 2020 Aug;56(8):1173-1177.

doi: 10.1111/jpc.15049. Epub 2020 Jul 31.

Authors

Affiliations

¹ Department of Rheumatology, The Sydney Children's Hospitals Network, Sydney, New South Wales, Australia.
² Paediatrics and Child Health, The University of Sydney, Sydney, New South Wales, Australia.
³ School of Maternal and Child Health, University of New South Wales, Sydney, New South Wales, Australia.
⁴ Department of Paediatrics, John Hunter Children's Hospital, Newcastle, New South Wales, Australia.
⁵ Department of Infectious Diseases, Alfred Health, Melbourne, Victoria, Australia.
⁶ School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia.
⁷ Paediatric Rheumatology, Starship Children's Hospital, Auckland, New Zealand.
⁸ University of Auckland, Paediatrics Child and Youth Health, Auckland, New Zealand.
⁹ Infection and Immunity, Murdoch Children's Research Institute, Melbourne, Victoria, Australia.
¹⁰ Immunisation Service, Royal Children's Hospital, Melbourne, Victoria, Australia.
¹¹ University of Melbourne, Melbourne, Victoria, Australia.
¹² Infectious Diseases University, Royal Children's Hospital, Melbourne, Victoria, Australia.
¹³ Department of Paediatrics, University of Melbourne, Melbourne, Victoria, Australia.
¹⁴ Department of Paediatrics, Monash University, Melbourne, Victoria, Australia.

PMID: 32735721
PMCID: PMC7436879
DOI: 10.1111/jpc.15049

Erratum in

Corrigendum.
[No authors listed] [No authors listed] J Paediatr Child Health. 2020 Sep;56(9):1490. doi: 10.1111/jpc.15195. J Paediatr Child Health. 2020. PMID: 32949201 Free PMC article. No abstract available.

Abstract

We provide an update on the state of play with regards a newly described inflammatory condition which has arisen during the current SARS-CoV-2 pandemic. The condition has been named paediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2 or multisystem inflammatory syndrome in children. This condition has shown significant similarities to Kawasaki disease and toxic shock syndrome.

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Comment on

Clinical Characteristics of 58 Children With a Pediatric Inflammatory Multisystem Syndrome Temporally Associated With SARS-CoV-2.
Whittaker E, Bamford A, Kenny J, Kaforou M, Jones CE, Shah P, Ramnarayan P, Fraisse A, Miller O, Davies P, Kucera F, Brierley J, McDougall M, Carter M, Tremoulet A, Shimizu C, Herberg J, Burns JC, Lyall H, Levin M; PIMS-TS Study Group and EUCLIDS and PERFORM Consortia. Whittaker E, et al. JAMA. 2020 Jul 21;324(3):259-269. doi: 10.1001/jama.2020.10369. JAMA. 2020. PMID: 32511692 Free PMC article.

References

1. European Centre for Disease Prevention and Control . Paediatric Inflammatory Multisystem Syndrome and SARS‐CoV‐2 Infection in Children, 18. Stockholm: The Centre; 2020.
1. CDC Health Alert Network . Multisystem Inflammatory Syndrome in Children (MIS‐C) Associated with Coronavirus Disease 2019 (COVID‐19). Center for Disease Control and Prevention; 2020. Report No.: CDCHAN‐00432. Available from: https://emergency.cdc.gov/han/2020/han00432.asp [accessed 26 May 2020].
1. WHO Global . Multisystem Inflammatory Syndrome in Children and Adolescents with COVID‐19. Geneva: World Health Organization; 2020. Report No.: WHO/2019‐nCoV/Sci_Brief/Multisystem_Syndrome_Children/2020.1. Available from: https://www.who.int/news‐room/commentaries/detail/multisystem‐inflammato... [accessed 26 May 2020].
1. Zimmermann P, Curtis N. Coronavirus infections in children including COVID‐19: An overview of the epidemiology, clinical features, diagnosis, treatment and prevention options in children. Pediatr. Infect. Dis. J. 2020; 39: 355–68. - PMC - PubMed
1. Dong Y, Mo X, Hu Y et al. Epidemiology of COVID‐19 among children in China. Pediatrics 2020; 145: e20200702. - PubMed

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Update on the COVID-19-associated inflammatory syndrome in children and adolescents; paediatric inflammatory multisystem syndrome-temporally associated with SARS-CoV-2

Affiliations

Update on the COVID-19-associated inflammatory syndrome in children and adolescents; paediatric inflammatory multisystem syndrome-temporally associated with SARS-CoV-2

Authors

Affiliations

Erratum in

Abstract

Comment on

References

Publication types

MeSH terms

LinkOut - more resources

Full Text Sources

Miscellaneous