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Review
. 2020 Sep;49(3):357-373.
doi: 10.1016/j.ecl.2020.06.002. Epub 2020 Jul 15.

Advances in the Imaging of Pituitary Tumors

James MacFarlane  1 , Waiel A Bashari  1 , Russell Senanayake  1 , Daniel Gillett  2 , Merel van der Meulen  1 , Andrew S Powlson  1 , Angelos Kolias  3 , Olympia Koulouri  1 , Mark Gurnell  4
Affiliations
Review

Advances in the Imaging of Pituitary Tumors

James MacFarlane et al. Endocrinol Metab Clin North Am. 2020 Sep.

Abstract

In most patients with pituitary adenomas magnetic resonance imaging (MRI) is essential to guide effective decision-making. T1- and T2-weighted sequences allow the majority of adenomas to be readily identified. Supplementary MR sequences (e.g. FLAIR; MR angiography) may also help inform surgery. However, in some patients MRI findings are 'negative' or equivocal (e.g. with failure to reliably identify a microadenoma or to distinguish postoperative change from residual/recurrent disease). Molecular imaging [e.g. 11C-methionine PET/CT coregistered with volumetric MRI (Met-PET/MRCR)] may allow accurate localisation of the site of de novo or persistent disease to guide definitive treatment (e.g. surgery or radiosurgery).

Keywords: (11)C-methionine; MRI; Met-PET/MR(CR); PET/CT; Pituitary adenoma.

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Conflict of interest statement

Disclosure The authors have nothing to disclose.

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