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Comment
. 2021 Jan 1;181(1):139-140.
doi: 10.1001/jamainternmed.2020.2438.

The Uncertain Role of Corticosteroids in the Treatment of COVID-19

Theodore G Liou  1   2   3 , Frederick R Adler  2   4   5 , Nathan D Hatton  3
Affiliations
Comment

The Uncertain Role of Corticosteroids in the Treatment of COVID-19

Theodore G Liou et al. JAMA Intern Med. .
No abstract available

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Conflict of interest statement

Conflict of Interest Disclosures: Dr Liou reported grants from the National Institutes of Health, the National Heart, Lung, and Blood Institute, the Cystic Fibrosis Foundation, the Iris M. and Ben B. Margolis Foundation, the Claudia Ruth Goodrich Stevens Endowment Fund, AbbVie, the Cystic Fibrosis Foundation Therapeutics Lab, Corbus Pharmaceuticals, Laurent Pharmaceuticals, Nivalis Therapeutics, Proteostasis Therapeutics, Savara, and Vertex Pharmaceuticals. No other disclosures were reported.

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References

    1. Wu C, Chen X, Cai Y, et al. Risk factors associated with acute respiratory distress syndrome and death in patients with coronavirus disease 2019 pneumonia in Wuhan, China. JAMA Intern Med. Published online March 13, 2020. doi:10.1001/jamainternmed.2020.0994 - DOI - PMC - PubMed
    1. Ruan S-Y, Lin H-H, Huang C-T, Kuo P-H, Wu H-D, Yu C-J. Exploring the heterogeneity of effects of corticosteroids on acute respiratory distress syndrome: a systematic review and meta-analysis. Crit Care. 2014;18(2):R63. doi:10.1186/cc13819 - DOI - PMC - PubMed
    1. Bosco JLF, Silliman RA, Thwin SS, et al. A most stubborn bias: no adjustment method fully resolves confounding by indication in observational studies. J Clin Epidemiol. 2010;63(1):64–74. doi:10.1016/j.jclinepi.2009.03.001 - DOI - PMC - PubMed
    1. Zhou F, Yu T, Du R, et al. Clinical course and risk factors for mortality of adult in patients with COVID-19 in Wuhan, China: a retrospective cohort study. Lancet. 2020;395(10229):1054–1062. doi:10.1016/S0140-6736(20)30566-3 - DOI - PMC - PubMed
    1. Collins R, Bowman L, Landray M, Peto R. The magic of randomization versus the myth of real-world evidence. N Engl J Med. 2020;382(7):674–678. doi:10.1056/NEJMsb1901642 - DOI - PubMed

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