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Comment
. 2020 Aug;10(8):1100-1102.
doi: 10.1158/2159-8290.CD-20-0494.

All Myeloid-Derived Suppressor Cells Are Not Created Equal: How Gender Inequality Influences These Cells and Affects Cancer Therapy

Dmitry I Gabrilovich  1
Affiliations
Comment

All Myeloid-Derived Suppressor Cells Are Not Created Equal: How Gender Inequality Influences These Cells and Affects Cancer Therapy

Dmitry I Gabrilovich. Cancer Discov. 2020 Aug.

Abstract

In this issue of Cancer Discovery, Bayik and colleagues demonstrated sexual dimorphism in accumulation of different populations of myeloid-derived suppressor cells in glioblastoma and showed that they could be targeted by different agents.See related article by Bayik et al., p. 1210.

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Conflict of interest statement

Conflict of interest disclosure:

Minor paid consultant for T-Rx Pharmaceutical, Quentis, Third Rock Venture, EMD Serono, Shattuck, Merck, Verseau Theraputic, Takeda, Riley FBR, Compass Theraputic, Elstar.

Figures

Figure
Figure
Sexual dimorphism of MDSC response in GBM
See this image and copyright information in PMC

Comment on

  • Myeloid-Derived Suppressor Cell Subsets Drive Glioblastoma Growth in a Sex-Specific Manner.
    Bayik D, Zhou Y, Park C, Hong C, Vail D, Silver DJ, Lauko A, Roversi G, Watson DC, Lo A, Alban TJ, McGraw M, Sorensen M, Grabowski MM, Otvos B, Vogelbaum MA, Horbinski C, Kristensen BW, Khalil AM, Hwang TH, Ahluwalia MS, Cheng F, Lathia JD. Bayik D, et al. Cancer Discov. 2020 Aug;10(8):1210-1225. doi: 10.1158/2159-8290.CD-19-1355. Epub 2020 Apr 16. Cancer Discov. 2020. PMID: 32300059 Free PMC article.

References

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