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. 2020 Jul 29;17(15):5481.
doi: 10.3390/ijerph17155481.

Effects of Prehospital Factors on Survival of Out-Of-Hospital Cardiac Arrest Patients: Age-Dependent Patterns

Bo Yoon Rhee  1 , Boram Kim  1 , Yo Han Lee  2
Affiliations

Effects of Prehospital Factors on Survival of Out-Of-Hospital Cardiac Arrest Patients: Age-Dependent Patterns

Bo Yoon Rhee et al. Int J Environ Res Public Health. .

Abstract

Many prehospital factors that are known to influence survival rates after out-of-hospital cardiac arrest (OHCA) have been rarely studied as to how their influence varies depending on the age. In this study, we tried to find out what prehospital factors affect the survival rate after OHCA by age groups and how large the effect size of those factors is in each age group. We used the South Korean OHCA registry, which includes information on various prehospital factors relating OHCA and final survival status. The association between prehospital factors and survival was explored through logistic regression analyses for each age group. The effects of prehospital factors vary depending on the patient's age. Being witnessed was relatively more influential in younger patients and the presence of first responders became more important as patients became older. While bystander cardiopulmonary resuscitation (CPR) did not appear to significantly affect survival in younger people, use of an automated external defibrillator (AED) showed the largest effect size on the survival in all age groups. Since the pathophysiology and etiologies of OHCA vary according to age, more detailed information on life support by age is needed for the development and application of more specialized protocols for each age.

Keywords: out-of-hospital cardiac arrest; prehospital factors; survival rates.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Process for selecting the study population.
Figure 2
Figure 2
Study framework. CPR, cardiopulmonary resuscitation; AED, automated external defibrillator.
See this image and copyright information in PMC

References

    1. Berdowski J., Berg R.A., Tijssen J.G., Koster R.W. Global incidences of out-of-hospital cardiac arrest and survival rates: Systematic review of 67 prospective studies. Resuscitation. 2010;81:1479–1487. doi: 10.1016/j.resuscitation.2010.08.006. - DOI - PubMed
    1. Nichol G., Thomas E., Callaway C.W., Hedges J., Powell J.L., Aufderheide T.P., Davis D. Regional variation in out-of-hospital cardiac arrest incidence and outcome. JAMA. 2008;300:1423–1431. doi: 10.1001/jama.300.12.1423. - DOI - PMC - PubMed
    1. Benditt D.G., Goldstein M., Sutton R., Yannopoulos D. Dispatcher-directed bystander initiated cardiopulmonary resuscitation: A safe step, but only a first step, in an integrated approach to improving sudden cardiac arrest survival. Circulation. 2010;121:10–13. doi: 10.1161/CIR.0b013e3181cd3c9f. - DOI - PubMed
    1. Cummins R.O., Ornato J.P., Thies W.H., Pepe P.E. Improving survival from sudden cardiac arrest: The “chain of survival” concept. A statement for health professionals from the Advanced Cardiac Life Support Subcommittee and the Emergency Cardiac Care Committee, American Heart Association. Circulation. 1991;83:1832–1847. doi: 10.1161/01.CIR.83.5.1832. - DOI - PubMed
    1. Marenco J.P., Wang P.J., Link M.S., Homoud M.K., Estes N.A. Improving survival from sudden cardiac arrest: The role of the automated external defibrillator. JAMA. 2001;285:1193–1200. doi: 10.1001/jama.285.9.1193. - DOI - PubMed