Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2020 Jul 30;12(8):829.
doi: 10.3390/v12080829.

Dengue: A Minireview

Harapan Harapan  1   2   3   4 , Alice Michie  4 , R Tedjo Sasmono  5 , Allison Imrie  4
Affiliations
Review

Dengue: A Minireview

Harapan Harapan et al. Viruses. .

Abstract

Dengue, caused by infection of any of four dengue virus serotypes (DENV-1 to DENV-4), is a mosquito-borne disease of major public health concern associated with significant morbidity, mortality, and economic cost, particularly in developing countries. Dengue incidence has increased 30-fold in the last 50 years and over 50% of the world's population, in more than 100 countries, live in areas at risk of DENV infection. We reviews DENV biology, epidemiology, transmission dynamics including circulating serotypes and genotypes, the immune response, the pathogenesis of the disease as well as updated diagnostic methods, treatments, vector control and vaccine developments.

Keywords: dengue; diagnosis; disease control; epidemiology; pathogenesis; treatment.

PubMed Disclaimer

Conflict of interest statement

The authors declare no conflict of interest. The funders had no role in the design of the study; in the collection, analyses, or interpretation of data; in the writing of the manuscript, or in the decision to publish the results.

References

    1. Go Y.Y., Balasuriya U.B.R., Lee C.K. Zoonotic encephalitides caused by arboviruses: Transmission and epidemiology of alphaviruses and flaviviruses. Clin. Exp. Vaccine Res. 2014;3:58–77. doi: 10.7774/cevr.2014.3.1.58. - DOI - PMC - PubMed
    1. Alatoom A., Payne D. An Overview of Arboviruses and Bunyaviruses. Labmedicine. 2009;40:237–240. doi: 10.1309/LMPX9OEOAOPPBCJH. - DOI
    1. Wilder-Smith A., Gubler D.J., Weaver S.C., Monath T.P., Heymann D.L., Scott T.W. Epidemic arboviral diseases: Priorities for research and public health. Lancet Infect. Dis. 2017;17:e101–e106. doi: 10.1016/S1473-3099(16)30518-7. - DOI - PubMed
    1. Gould E., Pettersson J., Higgs S., Charrel R., de Lamballerie X. Emerging arboviruses: Why today? One Health. 2017;4:1–13. doi: 10.1016/j.onehlt.2017.06.001. - DOI - PMC - PubMed
    1. Patterson J., Sammon M., Garg M. Dengue, Zika and Chikungunya: Emerging Arboviruses in the New World. West J. Emerg. Med. 2016;17:671–679. doi: 10.5811/westjem.2016.9.30904. - DOI - PMC - PubMed

Publication types

Substances